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Visar resultat 16 - 20 av 28 avhandlingar som matchar ovanstående sökkriterier.

  1. 16. Glomerular expression profiling and novel proteins in normal mouse kidney and adriamycin-induced nephrosis

    Författare :Masatoshi Nukui; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Kidney glomeruli function as high-capacity molecular sieves through which plasma is filtered into the Bowman s space as primary urine. The glomerular filtration barrier is composed of glomerular endothelial cells, the glomerulus basement membrane and the podocyte cell layer. LÄS MER

  3. 17. Nephrotic syndrome causes selective damage to the glomerular charge or size barriers. Physiological mechanisms based onexperimental studies in the rat

    Författare :Maria Ohlson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bikunin · capillary permeability · charge · Ficoll · glycocalyx · hyaluronan · isolated perfused kidney · kidney glomerulus · serum albumin;

    Sammanfattning : Nephrotic syndrome causes selective damage to the glomerular charge or size barriers. Physiological mechanisms based on experimental studies in the rat. Department of Physiology, Institute for Physiology and Pharmacology, Göteborg University, Box 432, SE-405 30 Gothenburg, Sweden. LÄS MER

  4. 18. Functional analysis of genes in the developing zebrafish pronephros and vasculature

    Författare :Lwaki Ebarasi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : During glomerulogenesis, the recruitment and assembly of visceral epithelial cells (podocytes), endothelial capillary cells, and smooth muscle pericytes (mesangial cells) result in the formation of the glomerular tuft. The mature glomerulus functions by passage of plasma under hemodynamic pressure across a filter, the glomerular filtration barrier, and the integrity of the barrier is crucial for proper function. LÄS MER

  5. 19. Diagnostic and prognostic value of proteinuria in chronic renal diseases

    Författare :Omran Bakoush; Njurmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Urology; Hypertension.; Glomerulonephritis; IgM; Albuminuria; Diabetic Nephropathy; nephrology; Urologi; nefrologi;

    Sammanfattning : To the extent that increased urinary protein excretion is an indicator of alterations of the glomerular capillary wall (GCW) and appearance of tubulointerstitial damage, proteinuria can be a good marker of the overall severity of the glomerular and tubulointerstitial damage, and therefore, the prognosis of glomerular diseases. Studies I, II, and III show that it is the type of proteinuria, rather than the degree of albuminuria, that predicts the progression in renal, proteinuric diseases. LÄS MER

  7. 20. Expression profiling of blood vessels in pericyte deficiency and diabetes

    Författare :Jenny Norlin; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The kidney glomerulus is essential for the filtration of waste products from the blood into the urine and in controlling the volume and composition of body fluids. Injury to the glomerulus can lead to altered glomerular filtration rate, proteinuria, thickening of the glomerular basement membrane (GBM) and accumulation of mesangial cell matrix. LÄS MER