Sökning: "Glomerular filtration barrier"

Visar resultat 1 - 5 av 26 avhandlingar innehållade orden Glomerular filtration barrier.

  1. 1. Dynamics of the glomerular filtration barrier - Physiological and pathophysiological aspects

    Författare :Josefin Axelsson; Njurmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glomerular filtration barrier; Glomerular permeability; Microalbuminuria; Albumin; Ficoll; Sieving Coefficient; Rats;

    Sammanfattning : The dynamic properties of the glomerular filtration barrier (GFB) are of fundamental importance for the understanding of the physiology and pathophysiology of microalbuminuria and proteinuric diseases. In the studies of this doctoral thesis the properties of the rat glomerular filtration barrier were investigated under resting conditions and following a number of challenges using highly sensitive gel filtration chromatography (HPSEC) detection of FITC-Ficoll in serum and urine. LÄS MER

  2. 2. Properties of the glomerular endothelial cell surface layer in vitro and in vivo

    Författare :Vincent Fridén; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :Glomerular filtration; Glomerular endothelial cell surface layer; Proteinuria; Proteoglycans; glycocalyx; glycosaminoglycans; glomerular endothelial cells; permselectivity and glomerular endothelial cell coat;

    Sammanfattning : A healthy kidney produces final urine that is practically devoid of proteins and other physiologically important solutes. Tremendous amounts of fluid are filtered every day through the glomerular filtration barrier which is the actual sieving site in the kidney. LÄS MER

  3. 3. Physiological aspects of the glomerular filtration barrier

    Författare :Kristinn Sverrisson; Njurmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Proteinuria is associated with progression of kidney disease and is an independent risk factor for cardiovascular morbidity and mortality. The pathophysiological alterations resulting in proteinuria are obscure, although proteinuria is often associated with pathological changes in the glomerular filtration barrier (GFB). LÄS MER

  4. 4. Experimental Studies on the Regulation of Glomerular Filtration Barrier Permeability In Vivo. Intra- and intercellular signaling mechanisms

    Författare :Julia Dolinina; Njurmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glomerular filtration barrier; Nitric Oxide; Endothelin-1; Angiotensin II; TRPC5; TRPC6 channel;

    Sammanfattning : .... LÄS MER

  5. 5. Characterization of novel podocyte proteins in the glomerular filtration barrier

    Författare :Laleh Sistani; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Sammanfattning : The kidney is considered the most important organ of excretion eliminating the body from metabolic waste products. The nephron is the functional unit of the kidney, composed of a cluster of capillaries named glomerulus, and a tubular system. The blood is filtered in the glomerular capillaries across the glomerular filtration barrier. LÄS MER