Sökning: "GRS"
Visar resultat 1 - 5 av 18 avhandlingar innehållade ordet GRS.
1. Genetics of Diabetes Subtypes. Characterization of novel cluster-based diabetes subtypes
Sammanfattning : BACKGROUND: Type 2 diabetes (T2D) has been reproducibly clustered into five subtypes based on six-clinical variables; age at diabetes onset, body mass index (BMI), Glutamic acid decarboxylase autoantibodies (GADA), glycated hemoglobin (HbA1c) and insulin secretion and resistance estimated as HOMA2B and HOMA2IR derived from fasting glucose and Cpeptide. These subtypes have different disease progression and risk of complications. LÄS MER
2. Fault tolerant control in flexible manufacturing systems
Sammanfattning : .... LÄS MER
3. Genetic and lifestyle influences on memory, brain structure, and dementia
Sammanfattning : This doctoral thesis investigated genetic, inflammatory, and lifestyle influences on cognition, brain structure, and dementia. The influence of TOMM40 polymorphisms (Study I), a PICALM, BIN1 and CLU genetic risk score (GRS; Studies II, III), and inflammatory cytokines (Study IV) was assessed, as well as potential interactions with physical activity (Studies II-IV). LÄS MER
4. Identification of genetic biomarkers for the risk prediction of recurrent venous thromboembolism. Risk prediction of recurrent VTE
Sammanfattning : Background: Venous thromboembolism (VTE) is the third most frequent life-threatening cardiovascular disease with an annual incidence rate of 1-2 per 1000 person-years. After the diagnosis for primary VTE, about 20-30% patients develop a recurrence within 5-years. LÄS MER
5. Genetic Determinants of Obesity in Relation to Diet, Weight Gain and Mortality
Sammanfattning : Obesity is one of the major health concerns that has reached epidemic proportions globally. It is generally believed to be a result of interactions between genetic and environmental factors. LÄS MER