Sökning: "GH secretion"

Visar resultat 26 - 30 av 58 avhandlingar innehållade orden GH secretion.

  1. 26. Growth hormone regulation of LFABP and PPARa. Genes involved in hepatic lipid metabolism

    Författare :Linda Carlsson; Göteborgs universitet; []
    Nyckelord :Growth hormone; fatty acids; rat; hepatocyte; LFABP; C EBPa; PPARa;

    Sammanfattning : Growth hormone (GH) is known to have several important effects in the control of metabolism. The aim of these studies was to investigate how GH regulates genes involved in fatty acid transport and metabolism in the liver and the interaction between GH and fatty acids in this regulation. LÄS MER

  3. 27. Cardiovascular effects of growth hormone, IGF-I and growth hormone secretagogues

    Författare :Åsa Tivesten; Göteborgs universitet; []
    Nyckelord :cardiovascular system; growth hormone; insulin-like growth factor-I; growth hormone secretagogues; echocardiography.;

    Sammanfattning : Growth hormone (GH) may exert direct growth-promoting and metabolic actions on target tissues, but most of its effects are mediated by circulating (endocrine) or local (auto-/paracrine) insulin-like growth factor-I (IGF-I). The GH/IGF-I system has an important role during cardiac development and for maintaining the structure and function of the heart. LÄS MER

  4. 28. The role of PPARalpha and growth hormone in hepatic lipid metaboism and atherosclerosis

    Författare :Anna Ljungberg; Göteborgs universitet; []
    Nyckelord :growth hormone; PPARalpha; atherosclerosis; lipid metabolism; fatty acids; apoB; ; ADRP; triglycerides; PGC-1; liver;

    Sammanfattning : Dyslipidemia mainly results from oversecretion of apoB-containing lipoproteins from theliver and is one of the most important risk factors for the development of atherosclerosis.Growth hormone (GH) plays a key role in the regulation of lipoprotein metabolism and thus,disturbances in GH secretion are associated with dyslipidemia and cardiovascular disease. LÄS MER

  5. 29. Bone Metabolism in Men

    Författare :Peter Gillberg; Olof Johnell; Uppsala universitet; []
    Nyckelord :Medical sciences; Male osteoporosis; Bone mineral density; Growth hormone; Insulin-like growth factors; Sex hormones; Growth hormone replacement; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

    Sammanfattning : In this thesis, the importance of the growth hormone (GH)/insulin-like growth factor (IGF) system and sex steroids for male bone metabolism has been investigated, and the effects of continuous low dose GH replacement in GH deficient (GHD) adults. In a population-based sample of men, positive correlations were found between bone mineral density (BMD) and IGF-I, IGF-II, IGF binding protein (IGFBP)-3 and the testosterone/sex hormone binding globulin (SHBG) ratio. LÄS MER

  7. 30. Studies on growth hormone regulation of the CYP2C12 gene in rat liver

    Författare :Hanna Helander; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Growth hormone (GH) is secreted from the pituitary gland in a sexually dimorphic manner in the rat. This leads to a sexual dimorphism in the expression of a number of hepatic GH-target genes including members of the cytochrome P450 (CYP) family. LÄS MER