Sökning: "Drosophila embryo"

Visar resultat 11 - 15 av 19 avhandlingar innehållade orden Drosophila embryo.

1. 11. Investigating the function of the Receptor Tyrosine Kinase ALK during Drosophila melanogaster development

   Författare :Christina Lorén; Mike Taylor; Umeå universitet; []
   Nyckelord :DAlk; receptor tyrosine kinase; Jeb; visceral muscle fusion; ERK; Drosophila; endoderm; molecular cell biology; molekylär cellbiologi;

   Sammanfattning : The Drosophila melanogaster gene Anaplastic Lymphoma Kinase (DAlk) is homologous to mammalian Alk, which is a member of the Alk/Ltk family of receptor tyrosine kinases (RTKs). In humans the t(2;5) translocation involving the Alk locus encodes an active form of Alk that is the causative agent in Non-Hodgkin’s Lymphoma (Morris et al., 1994). LÄS MER

3. 12. Revisiting cell specification and differentiation in the Drosophila airways, an insect organ homologous to our lung and blood vessels

   Författare :Ryo Matsuda; Christos Samakovlis; Payre Francois; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; cell differentiation; airways; Drosophila; cell signaling; transcription factors; utvecklingsbiologi; Developmental Biology;

   Sammanfattning : Oxygen is essential for life. Aquatic ancestral animal species are thought to have independently terrestrialized and invented distinct strategies for efficient oxygen supply. The respiratory system of vertebrates like us is composed of lungs connected to the vasculature while insects have a single system delivering air directly to internal tissues. LÄS MER

4. 13. Towards forecasting epigenetic repression

   Författare :Moa J. Lundkvist; Yuri B. Schwartz; Ludvig Lizana; Peter V. Kharchenko; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; epigenetics; Polycomb; PRC1; PRC2; H3K27 methylation; Monte-Carlo simulation; chromatin structure; Drosophila; molekylär bioteknik inst f molekylärbiologi ; molecular biotechnology dept of molecular biology ;

   Sammanfattning : Multicellular organisms form many different cell types from one genome, which requires differential gene activity. The Polycomb system upholds the correct gene expression programs by epigenetically silencing genes that encode critical transcription regulators. LÄS MER

5. 14. Short and long-term effects of exposure to low dose and low dose rate of gamma radiation : using in vitro and in vivo models

   Författare :Traimate Sangsuwan; Siamak Haghdoost; Eva Forssell-Aronsson; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Low dose; Low dose rate; High dose rate; Ionizing radiation; Adaptive response; Senescence; Premature senescence; Oxidative stress; Drosophila embryo; Mutation; DNA repair; molekylär biovetenskap; Molecular Bioscience;

   Sammanfattning : Assessment of human health risks from exposure to ionizing radiation (IR) is mainly based on the extrapolation of results from epidemiological studies on populations exposed to relatively high doses and often at high dose rates (HDR). Risk estimates after exposure to low doses and in particular at low dose rates (LDR) remain controversial due to a lack of epidemiological evidence. LÄS MER

7. 15. Suppressor of zeste 12, a Polycomb group gene in Drosophila melanogaster; one piece in the epigenetic puzzle

   Författare :Anna Birve; Anssi Saura; Allen Shearn; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Drosophila melanogaster; epigenetic; homeotic genes; Polycomb group; PRE; heterochromatin; Suppressor of zeste 12; chromatin silencing; Genetik; Clinical genetics; Klinisk genetik; Genetics; genetik;

   Sammanfattning : In multicellular organisms all cells in one individual have an identical genotype, and yet their bodies consist of many and very different tissues and thus many different cell types. Somehow there must be a difference in how genes are interpreted. So, there must be signals that tell the genes when and where to be active and inactive, respectively. LÄS MER