Sökning: "DAlk"

Hittade 2 avhandlingar innehållade ordet DAlk.

1. 1. Investigating the function of the Receptor Tyrosine Kinase ALK during Drosophila melanogaster development

   Författare :Christina Lorén; Mike Taylor; Umeå universitet; []
   Nyckelord :DAlk; receptor tyrosine kinase; Jeb; visceral muscle fusion; ERK; Drosophila; endoderm; molecular cell biology; molekylär cellbiologi;

   Sammanfattning : The Drosophila melanogaster gene Anaplastic Lymphoma Kinase (DAlk) is homologous to mammalian Alk, which is a member of the Alk/Ltk family of receptor tyrosine kinases (RTKs). In humans the t(2;5) translocation involving the Alk locus encodes an active form of Alk that is the causative agent in Non-Hodgkin’s Lymphoma (Morris et al., 1994). LÄS MER

3. 2. Protein tyrosine kinases and the regulation of signalling and adhesion in drosophila melanogaster

   Författare :Caroline Grabbe; Ruth Palmer; Tapio Heino; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Drosophila; Signalling; Adhesion; Protein Tyrosine Kinase; Development; Endocytosis; Molecular biology; Molekylärbiologi;

   Sammanfattning : In order to build a multi-cellular organism and to regulate cellular functions, cells need to communicate with each other, as well as tightly regulate their behaviour in response to environmental changes. For these purposes all eukaryotic cells express a large number of membrane spanning receptors that either themselves contain catalytic activity or via cytoplasmic effector enzymes, function to transmit “signals” from the cell exterior to induce appropriate responses within the cell. LÄS MER