Sökning: "Cushing’s syndrome"
Visar resultat 1 - 5 av 8 avhandlingar innehållade orden Cushing’s syndrome.
1. Clinical challenges in Cushing's syndrome
Sammanfattning : Cushing’s syndrome (CS) is caused by prolonged exposure to cortisol excess. CS is associated with cardiovascular diseases, infections, and fractures, as well as with cognitive impairment and affective disorders. LÄS MER
2. Glucocorticoids - outcome in patients with glucocorticoid deficiency and Cushing's syndrome
Sammanfattning : Glucocorticoids (GCs) are steroid hormones that have a major impact on human metabolism and are essential for life. Chronic GC overexposure, called Cushing’s syndrome, is characterized by central obesity, muscle atrophy, osteoporosis, hypertension, impaired glucose tolerance and neurocognitive impairment. LÄS MER
3. Diagnosing hyper- and hypocortisolism using saliva samples : pitfalls and how to avoid them
Sammanfattning : Background: Cushing's syndrome (CS) is caused by high cortisol secretion whereas insufficient cortisol secretion is called adrenal insufficiency (AI). Both are rare diseases with substantial diagnostic delay, and high morbidity and mortality even though effective treatment is available. LÄS MER
4. Cushing’s disease and aggressive pituitary tumours : Aspects on epidemiology, treatment, and long-term follow-up
Sammanfattning : This thesis focuses on clinical and epidemiological aspects of aggressive pituitary tumours/carcinomas and Cushing’s disease. Pituitary carcinomas account for only 0.1-0. LÄS MER
5. Glucocorticoid administration : studies on weight regulation and metabolic implications
Sammanfattning : Long-term treatment with glucocorticoids induces weight gain and increased risk to develop obesity-related metabolic complications like insulin resistance, type 2 diabetes and cardiovascular disease. Glucocorticoids have been suggested to play a role in development of visceral fat accumulation. LÄS MER