Sökning: "Congenic"

Visar resultat 21 - 25 av 72 avhandlingar innehållade ordet Congenic.

  1. 21. Genetic regulation of autoantibodies in arthritis : lessons from mouse models

    Författare :Bruno Raposo; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Autoimmune diseases such as rheumatoid arthritis (RA) or multiple sclerosis (MS) are commonly regarded as complex or multifactorial diseases. This complexity regards to effector mechanisms involved in pathologic manifestations, and also to the diversity of genetic and environmental factors that predispose individuals to such diseases. LÄS MER

  3. 22. Genetics in experimental traumatic brain injury

    Författare :Faiez Al Nimer; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Traumatic brain injury (TBI) is the leading cause of death and disability in the young population in the industrialized world. It comprises a heterogeneous group of brain pathologies where head trauma initiates a series of complex molecular pathways, which, together with the initial injury, account for the final outcome. LÄS MER

  4. 23. From genes to function in autoimmunity : a salty story

    Författare :Daniëlle Vaartjes; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Autoimmunity is a condition in which the ability to tolerate self breaks down, resulting in immune responses against the body’s own healthy cells and tissues. Autoimmune diseases are complex and multifactorial, and both genetic and environmental factors are known to play a crucial role. LÄS MER

  5. 24. The complex genetics of experimental autoimmune neuroinflammation

    Författare :Maja Jagodic; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :EAE; MS; QTL; AIL; linkage analysis; gene regulation;

    Sammanfattning : Experimental autoimmune encephalomyelitis (EAE) is an animal model for multiple sclerosis (MS), a chronic inflammatory and demyelinating disease of the central nervous system (CNS). MS is the second most common cause of neurological disability among young adults in the western world. LÄS MER

  7. 25. Identification of Arthritis Susceptibility Genes in Mice and Humans

    Författare :Emma Ahlqvist; Immunologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunologi; transplantation; serology; Immunology; Medicin människa och djur ; Medicine human and vertebrates ; Biomedicinska vetenskaper; QTL; Biomedical sciences; Rheumatoid arthritis; Collagen-induced arthritis; serologi; Skeleton; muscle system; rheumatology locomotion; Skelett; muskelsystem; reumatologi; Clinical genetics; Klinisk genetik;

    Sammanfattning : Rheumatoid arthritis (RA) is a chronic autoimmune disease with a largely unknown aetiology. The risk of developing RA is partly dependent on genetic factors, which has motivated extensive efforts to identify the disease regulating genes as away to understand disease pathogenesis. LÄS MER