Sökning: "Comparative Genomics"

Visar resultat 16 - 20 av 76 avhandlingar innehållade orden Comparative Genomics.

1. 16. Comparative genomics of the genus Mycobacterium : Genome evolution, phylogeny and diversity

   Författare :Phani Rama Krishna Behra; Leif Kirsebom; Bengt Persson; Mikael Rhen; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Mycobacterial genomes; core gene phylogeny; tRNA and non-coding RNA; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi;

   Sammanfattning : The genus Mycobacterium includes more than 190 species, and many cause severe diseases such as tuberculosis and leprosy. According to the "World Health Organization", in year 2019 alone, 10 million people developed TB, and 1.4 million died. LÄS MER

3. 17. Exploration of microbial diversity and evolution through cultivation independent phylogenomics

   Författare :Joran Martijn; Thijs J.G. Ettema; Andrew Roger; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; cultivation independent genomics; metagenomics; single-cell genomics; metagenomic binning; phylogenetics; phylogenomics; phylogenetic artefacts; comparative genomics; gene tree-species tree reconciliation; rRNA amplicon sequencing; Tara Oceans; origin of mitochondria; Alphaproteobacteria; Rickettsiales; Haloarchaea; endosymbiosis; Biologi med inriktning mot molekylär evolution; Biology with specialization in Molecular Evolution;

   Sammanfattning : Our understanding of microbial evolution is largely dependent on available genomic data of diverse organisms. Yet, genome-sequencing efforts have mostly ignored the diverse uncultivable majority in favor of cultivable and sociologically relevant organisms. LÄS MER

4. 18. Novel resources enabling comparative regulomics in forest tree species

   Författare :David Sundell; Torgeir Hvidsten; Klaas Vandepoele; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Comparative genomics; Web resource; Wood development; RNA-Seq; Forestry; Lignocellulose; Regulomics; High-spatial resolution; Populus tremula; Picea abies; Orthology.; biology; biologi; molekylär bioteknik inst f nat vet biokemi ; molecular biotechnology dept of biochem ;

   Sammanfattning : Lignocellulosic plants are the most abundant source of terrestrial biomass and are one of the potential sources of renewable energy that can replace the use of fossil fuels. For a country such as Sweden, where the forest industry accounts for 10% of the total export, there would be large economical benefits associated with increased biomass yield. LÄS MER

5. 19. Investigation of Mechanics of Mutation and Selection by Comparative Sequencing

   Författare :Michael C. Zody; Kerstin Lindblad-Toh; Leif Andersson; Chad Nusbaum; Henrik Kaessmann; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; chicken; chimpanzee; human; evolution; segmental duplication; structural variation; chromosomal rearrangement; comparative genomics; positive selection; selective sweep; Genetics; Genetik; Genetics; genetik;

   Sammanfattning : The process of evolution is of both scientific and medical interest. This thesis presents several studies using complete genomic reference sequences, comparative genomic data, and intraspecific diversity data to study the two key processes of evolution: mutation and selection. LÄS MER

7. 20. Evolution of symbiotic lineages and the origin of new traits

   Författare :Daniel Tamarit; Siv G. E. Andersson; Lisa Klasson; Amparo Latorre; Julian Parkhill; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; symbiosis; host-association; Lactobacillus; Bifidobacterium; Rhizobiales; Bartonella; honeybees; ants; codon usage bias; genome architecture; genome organization; gene transfer agent; evolutionary genomics; comparative genomics; Biologi med inriktning mot molekylär evolution; Biology with specialization in Molecular Evolution; Biology with specialization in Evolutionary Genetics; Biologi med inriktning mot evolutionär genetik; Biologi med inriktning mot mikrobiologi; Biology with specialization in Microbiology;

   Sammanfattning : This thesis focuses on the genomic study of symbionts of two different groups of hymenopterans: bees and ants. Both groups of insects have major ecological impact, and investigating their microbiomes increases our understanding of their health, diversity and evolution. LÄS MER