Sökning: "Clearance rate"

Visar resultat 36 - 40 av 146 avhandlingar innehållade orden Clearance rate.

  1. 36. The B lymphocyte in Staphylococcus aureus arthritis

    Författare :Inger Gjertsson; Göteborgs universitet; []
    Nyckelord :Staphylococcus aureus; mice; arthritis; sepsis; B cells; Fcg receptors; CD22; ; IL-4; IL-10; IFN-g.;

    Sammanfattning : Joint infection caused by Staphylococcus aureus leads to heavy synovitis and rapid destruction of bone and cartilage. Permanent loss of joint function is seen in 20-50% of the patients, despite early eradication of the bacteria with antibiotics. LÄS MER

  3. 37. Bird-parasite interactions : Using Sindbis virus as a model system

    Författare :Karin M. Lindström; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; Carduelis chloris; Sindbis virus; host-parasite interaction; ornament; social dominance; testosterone; sexual selection; Utvecklingsbiologi; Developmental biology; Utvecklingsbiologi; populationsbiologi; Population Biology;

    Sammanfattning : This thesis focuses on the evolutionary interactions between birds and a parasite, the mosquito-borne Sindbis virus (Togaviridae, Alphavirus). In conclusion, the results show that the Sindbis virus is widespread among birds, and that the fitness of infected hosts may be reduced by the virus. LÄS MER

  4. 38. Turnover of chylomicrons in the rat

    Författare :Magnus Hultin; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Mechanisms involved in the clearance of chylomicrons and aspects of the interactions at the vascular endothelium were studied in the rat.The poly-anion heparin, known to release lipoprotein lipase (LPL) from the vascular endothelium, enhanced the clearance of chylomicrons. LÄS MER

  5. 39. The pharmacokinetics and pharmacodynamics of clevidipine, a new ultrashort-acting calcium antagonist, in different animal species and man

    Författare :Hans Ericsson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacy; FARMACI; PHARMACY; FARMACI; Biopharmaceutics; biofarmaci;

    Sammanfattning : Clevidipine is a new ultrashort-acting calcium antagonist of the dihydropyridine type developed for reduction and control of blood pressure in connection with cardiac surgery. The aim of this thesis was to characterise the in vitro hydrolysis rate of clevidipine in different biological matrices and the pharmacokinetics and pharmacodynamics in animal species and various human populations. LÄS MER

  7. 40. Monitoring cystic fibrosis lung disease in children - Clinical utility and associations between functional and structural methods

    Författare :Marcus Svedberg; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cystic fibrosis; children; lung disease;

    Sammanfattning : Background: Cystic Fibrosis (CF) is an inherited progressive disease that causes severe damage to the airways and other organs of the body. Many methods are available to track CF lung disease but longitudinal data are needed to better understand the clinical utility and associations between different methods. LÄS MER