Sökning: "Citalopram"

Visar resultat 11 - 15 av 40 avhandlingar innehållade ordet Citalopram.

1. 11. PET studies of the serotonin transporter in the human brain

   Författare :Johan Lundberg; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :positron emission tomography; MADAM; WAY 100635; 5-HTT; 5-HT1A receptors; receptor occupancy; major depressive disorder; citalopram; escitalopram;

   Sammanfattning : The serotonin (5-HT) system attracts considerable attention in research on the pathophysiology and drug treatment of neuropsychiatric disorders. The brain imaging technique Positron Emission Tomography (PET) allows for examination of neurotransmission systems in the human brain in vivo. LÄS MER

3. 12. Parkinson’s disease and depression : clinical and neurobiological studies

   Författare :Sven E Pålhagen; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Parkinson´s disease. Major depressive disorder; SSRI; rCBF; CSF-biomarker;

   Sammanfattning : Parkinson´s disease (PD) is a progressive degenerative movement disorder. PD patients also suffer from several non-motor symptoms including autonomic disturbances, cognitive decline and neuropsychiatric conditions. LÄS MER

4. 13. CYP2C19 polymorphisms in drug metabolism and response

   Författare :Ming Chang; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Individuals vary widely in their response to drug treatment. After receiving doses of a drug that are recommended based on a population average, some patients could have an insufficient response, whereas others may experience adverse effects. LÄS MER

5. 14. Neurobiological aspects of human aging and suicide

   Författare :Belén Arranz; Lil Träskman-Bendz; Linköpings universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : This thesis addresses: 1) The involvement of the monoaminergic and neuropeptidergic neurotransmitter systems in the aging process, and 2) The contribution of these systems in the etiology of an age-related mental disorder: the depressive syndrome. Because of the evidence suggesting the efficacy of the SSRI in the treatment of some age-related symptoms, a comparison study of the binding characteristics of two SSRI, i. LÄS MER

7. 15. Characterization of secretory mechanisms in lacrimal and salivary glands

   Författare :Martin Dankis; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; dry mouth; dry eyes; antidepressant; muscarinic; purinergic; salivary secretion; tear secretion; lacrimal gland; in vivo; primary culture; co-culture; acinar; myoepithelial;

   Sammanfattning : Dry mouth and dry eyes are multifactorial morbidities that can lead to a severely reduced quality of life. Approximately 20% of the population suffers from ocular or oral dryness. LÄS MER