Sökning: "Cervical neoplasia"

Visar resultat 6 - 10 av 40 avhandlingar innehållade orden Cervical neoplasia.

1. 6. Non-attendees need attention - Determinants and interventions affecting participation in cervical cancer screening

   Författare :Gudrun Broberg; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cervical cancer; Cervical intraepithelial neoplasia; Demography; HPV; Mass screening; Non-attendance; Papanicolaou smear; Telephone call; Socioeconomic factors;

   Sammanfattning : Aim: Non-attendance is the foremost screening-related risk factor for cervical cancer. The overall aim of this thesis is to contribute to preventing cervical cancer by focusing attention on non-attendees, assessing interventions to increase participation in screening and identifying determinants for non-attendance. LÄS MER

3. 7. Molecular Pathogenesis of Cervical Carcinoma : Analysis of Clonality, HPV16 Sequence Variations and Loss of Heterozygosity

   Författare :Xinrong Hu; Björn Hagmar; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; cervical carcinoma; CIN; HPV; LOH; X-chromosome inactivation; clonality; molecular pathogenesis; Genetik; Clinical genetics; Klinisk genetik; Pathology; patologi;

   Sammanfattning : A previous model of morphological pathogenesis assumed that cervical carcinoma is of monoclonal origin and progresses through multiple steps from normal epithelium via CINS into invasive carcinomas. The aim of this study was to investigate the molecular mechanism of pathogenesis of cervical neoplasia. LÄS MER

4. 8. Tissue tumor marker expression in normal cervical tissue and in cervical intraepithelial neoplasia, for women who are at high risk of human papilloma virus infection, are smokers, contraceptive users or in fertile age

   Författare :Raghad Samir; Dan Hellberg; Anna Asplund; Pär Sparen; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tumor markers; cervical intraepithelial neoplasia; smoking; contraceptive use; sex steroid hormones; HPV infection; Obstetrik och gynekologi; Obstetrics and Gynaecology;

   Sammanfattning : The aim of this research was to study the correlation between tissue tumor marker expression and HR-HPV infection, smoking, hormonal contraceptive use and sex steroids in women with cervical intraepithelial neoplasia or normal epithelium. The study investigated the expression of 11 tumor markers in cervical biopsies obtained from 228 women with different diagnoses ranging from normal cervical epithelium to various stages of CIN. LÄS MER

5. 9. Cervical intraepithelial neoplasia in migrant women living with HIV

   Författare :Christina Carlander; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The aim of this thesis was to study high-grade cervical intraepithelial neoplasia (CIN) in women living with HIV (WLWH) in Sweden compared with HIV-negative women (HNW) of the same region of birth. In Paper I we assessed the cumulative incidence (CuI) and hazard ratio (HR) of CIN3, adenocarcinoma, and invasive cervical cancer (CIN3+) in a cohort of WLWH (n = 893) and HNW (n = 205 842) by linking the Swedish national HIV registry (InfCare HIV) with the Swedish Population Registry (SPR) and the Swedish National Cervical Screening Registry (NKCx). LÄS MER

7. 10. Self-sampling for HPV testing in primary cervical screening : Including clinical and health economic aspects

   Författare :Riina Aarnio; Matts Olovsson; Ulf B. Gyllensten; Ingrid Wikström; Christer Borgfeldt; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HPV; self-sampling; cervical screening; CIN2 ; cost-effectiveness; Obstetrik och gynekologi; Obstetrics and Gynaecology;

   Sammanfattning : Persistent infection with high-risk human papillomavirus (HPV) is a prerequisite for the development of cervical cancer. HPV testing has higher sensitivity for high-grade cervical intraepithelial neoplasia (CIN2+) than cytology, resulting in more effective screening. LÄS MER