Sökning: "CIN2"

Visar resultat 1 - 5 av 12 avhandlingar innehållade ordet CIN2.

  1. 1. Self-sampling for HPV testing in primary cervical screening : Including clinical and health economic aspects

    Författare :Riina Aarnio; Matts Olovsson; Ulf B. Gyllensten; Ingrid Wikström; Christer Borgfeldt; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HPV; self-sampling; cervical screening; CIN2 ; cost-effectiveness; Obstetrik och gynekologi; Obstetrics and Gynaecology;

    Sammanfattning : Persistent infection with high-risk human papillomavirus (HPV) is a prerequisite for the development of cervical cancer. HPV testing has higher sensitivity for high-grade cervical intraepithelial neoplasia (CIN2+) than cytology, resulting in more effective screening. LÄS MER

  2. 2. Cervical cancer prevention Studies on possible improvements

    Författare :Björn Strander; Göteborgs universitet; []
    Nyckelord :Cervical intraepithelial neoplasia; cytology; colposcopy; HPV; cervical neoplasm; epidemiology; treatment; follow up;

    Sammanfattning : Aims: The aim of this study is to target and assess possible improvements for women attending cervical cancer screening programs. Methods: In a randomized study the use of ThinPrep liquid based cytology (LBC) was tested against conventional cytology. LÄS MER

  3. 3. Cervical intraepithelial neoplasia in migrant women living with HIV

    Författare :Christina Carlander; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The aim of this thesis was to study high-grade cervical intraepithelial neoplasia (CIN) in women living with HIV (WLWH) in Sweden compared with HIV-negative women (HNW) of the same region of birth. In Paper I we assessed the cumulative incidence (CuI) and hazard ratio (HR) of CIN3, adenocarcinoma, and invasive cervical cancer (CIN3+) in a cohort of WLWH (n = 893) and HNW (n = 205 842) by linking the Swedish national HIV registry (InfCare HIV) with the Swedish Population Registry (SPR) and the Swedish National Cervical Screening Registry (NKCx). LÄS MER

  4. 4. Human papillomavirus and cervical cancer : detection of potential markers of disease progression using liquid-based cytology

    Författare :Ingrid Norman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : This protect aims to evaluate alternative strategies to screen for cervical cancer including liquid-based cytology (LBC) with supplementary reflex testing for human papillomavirus (HPV), p16INK4a, HPV-L1 capsid protein, and miR-205 for use as possible diagnostic and prognostic markers in women with abnormal findings detected through the organized cervical cancer screening program. This split-sample study enrolled 137 women with atypical Pap smear findings to compare the effectiveness of conventional cytology (CC) with LBC cytology for cervical cancer screening. LÄS MER

  5. 5. Prevention of cervical cancer through use of liquid-based cytology and supplementary HPV testing in population-based screening

    Författare :Maria Fröberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The aim of this project is to evaluate an alternative screening strategy using liquid- based cytology (LBC), and supplementary detection of human papillomavirus (HPV) in cases of minor cytological abnormalities (atypical squamous cells of undetermined significance, ASCUS, and low-grade squamous intraepithelial lesion, LSIL). Within population-based screening in Stockholm, Sweden, we alternated screening using LBC with supplementary HPV testing in ASCUS and LSIL (LBC+HPV testing, using Linear Array HPV genotyping Assay, Roche diagnostics) and conventional cytology (CC), from September 2005 to December 2006. LÄS MER