BIOACTIVE SECONDARY METABOLITES -Isolation Characterization and Synthesis

Detta är en avhandling från Organic chemistry (S/LTH), Lund University

Sammanfattning: Nature produces biologically active and chemically intriguing secondary metabolites. To isolate and characterize compounds of novel activity and structure, bioassay-guided fractionations were applied to several plants as well as to a basidiomycete. Our studies resulted in the purification and characterization of a diverse range of compounds displaying activity in a variety of biological assays. New secondary metabolites and semi-synthetic compounds were obtained from Bolivian species Piper heterophyllum, Piper obliquum, Piper longestylosum and Baccharis genistelloides, from the European species Myrtus communis, Thapsia garganica and from the basidiomycete Coprinus heptemerus.

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