Sökning: "work env"
Visar resultat 1 - 5 av 9 avhandlingar innehållade orden work env.
1. Repertoire diversity and maturation of HIV-1 vaccine-induced B cell responses
Sammanfattning : In the work presented in this thesis, I characterized B cell responses in rhesus macaques inoculated with HIV-1 envelope glycoprotein (Env)-based vaccines to define genetic and functional properties of the elicited antibodies for an improved understanding of Env immunogenicity. In Paper I, we investigated antibody heavy chain V gene segment expression in the overall B cell repertoire and in response to vaccination by using 2 approaches, 454-pyrosequencing and single-cell RT-PCR of bulk and sorted memory B cells, respectively. LÄS MER
2. HIV disease progression - Impact of HIV-1 intersubtype recombination and association with HIV-2 evolution
Sammanfattning : Human immunodeficiency virus type 1 (HIV-1) and type 2 (HIV-2) are both causative agents of AIDS, with similar pathogenic characteristics. However, the rate of disease progression is highly variable both within and between HIV-1 and HIV 2, but the mechanisms involved in modulating the rate of disease progression remain poorly understood. LÄS MER
3. Patch loading of stainless steel girders : experiments and finite element analyses
Sammanfattning : This thesis deals with the behaviour of stainless steel girders subjected to patch loading. The current loading situation arises for example at beam- column connections or at crane girders where the load is travelling along a girder. At bridge launching it is also important to consider patch loading. LÄS MER
4. The revolutionary partnership of computation and biology
Sammanfattning : The organization of living beings is complex. Science uses modeling in order to gain a deeper understanding, and to be able to manipulate the processes of living organisms. To this purpose, I used and developed computational tools to investigate and model different relevant biological phenomena. LÄS MER
5. Studies on the barrier properties of exterior wood coatings
Sammanfattning : Coatings for exterior wood have two basic functions. One isto give an aesthetically acceptable surface appearance andcolour. The other is to provide protection against wooddegradation by microbiological or physical attack. LÄS MER