Sökning: "viral factors"

Visar resultat 26 - 30 av 306 avhandlingar innehållade orden viral factors.

  1. 26. Viral and host determinants in hepatitis B

    Författare :Hossein Sendi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The outcome of hepatitis B infection is highly variable, ranging from acute disease resulting in the elimination of infection to persistent infection that can lead to cirrhosis or hepatocellular carcinoma. The factors determining the outcome in an individual are not fully known but may be classified into viral and host factors. LÄS MER

  3. 27. Factors influencing the evolution of HIV-1

    Författare :Markus Birk; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :HIV; antiretroviral treatment; evolution; gag; pol; env;

    Sammanfattning : Due to the high replication rate and the low fidelity of the viral reverse transcriptase (RT), various mutations are introduced continuously into the gene pool of HIV-1. Together with recombination events this leads to the evolution of countless quasispecies. LÄS MER

  4. 28. Characterizing important flavivirus-host interactions : Replication, assembly, restriction factors and vaccine development

    Författare :Pham Tue Hung Tran; Magnus Johansson; Wessam Melik; Naveed Asghar; Sören Andersson; Laurent Chatel-Chaix; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Flaviviruses; virus-host cell interaction; lunapark; ESCRT; ALIX; CHMP4A; ISG15; TRIMs; replicon virus-like particles; vaccine;

    Sammanfattning : The genus Flavivirus (family Flaviviridae) consists of important zoonotic viruses that cause morbidity and mortality worldwide. These viruses are enveloped and have a positive-sense single-stranded RNA genome encoding a polyprotein. LÄS MER

  5. 29. Risk and prognostic factors for malignant glioma

    Författare :Sara Sjöström; Beatrice S Melin; Ulrika Andersson; Monika Hegi; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glioma; Glioblastoma; Risk; Outcome; EGR; EGFR; VEGF; VEGFR; DNA repair; virus; Oncology; Onkologi; onkologi; Oncology;

    Sammanfattning : Background: Glioblastoma is the most common and aggressive type of glioma and associated with poor prognosis. Apart from ionizing radiation and some rare genetic disorders, few aetiological factors have been identified for primary brain tumours. LÄS MER

  7. 30. Physics of Viral Infectivity: Energetics of Genome Ejection

    Författare :Meerim Jeembaeva; Biokemi och Strukturbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; microfluidics.; differential scanning calorimetry; capsid; Key words: phage; osmotic suppression; DNA ejection; isothermal titration calorimetry; enthalpy;

    Sammanfattning : All viruses that infect bacteria, plant, or animal cells involve a genome (RNA or DNA) that is encapsidated by a rigid protein shell. After delivery of the viral genome into the host cell, new capsid proteins, which are encoded by viral DNA or RNA, are expressed and self-assembled into new viral capsids. LÄS MER