Sökning: "viral factors"

Visar resultat 6 - 10 av 305 avhandlingar innehållade orden viral factors.

  1. 6. Hox transcription factors in hematopoiesis

    Författare :Jon Mar Björnsson; Avdelningen för molekylärmedicin och genterapi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; extracellular fluids; Hematologi; extracellulära vätskor; Haematology; hematopoies; tet; Hox; cre lox;

    Sammanfattning : Hematopoiesis is a lifelong, dynamic process in which a small number of pluripotent hematopoietic stem cells (HSC) residing in the bone marrow (BM) give rise to billions of mature blood cells of both myeloid and lymphoid origin each day. This enormous capacity of HSC has been utilized in BM transplantations for 4 decades and is also very important for future gene therapy. LÄS MER

  3. 7. Early life cytokines, viral infections and IgE-mediated allergic disease

    Författare :Anna-Karin Larsson; Marita Troye-Blomberg; Gunnar Lilja; Maria Jenmalm; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; IgE-sensitisation; childhood; cytokine; viral infection; atopy; single nucleotide polymorphism; cord blood; Immunology; Immunologi;

    Sammanfattning : Background: The reasons why some individuals become IgE-sensitised and allergic are largely unknown, though genetic- and early life environmental factors seem to be of importance.Objective: The overall aim of this thesis was to investigate the relationship between IgE-sensitisation and allergic disease, viral infections, genetic markers and early life cytokines. LÄS MER

  4. 8. Human papillomavirus tropism : determinants of viral tissue specificity

    Författare :Nitesh Mistry; Magnus Evander; Ola Forslund; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; papillomavirus; receptor; heparan sulfate; pI; lactoferrin; lactoferricin; transcription; long control region; tropism; Virology; Virologi;

    Sammanfattning : Cervical cancer is the second most common cancer among women worldwide and human papillomavirus (HPV) is a prerequisit for the development of this cancer. HPV belongs to the Papillomaviridae family and infects the basal layer of epithelial cells where it generally progresses into warts or condylomas. LÄS MER

  5. 9. Early cervical lesions detected by visual inspection : viral factors, management and follow-up

    Författare :Twaha Serunjogi Mutyaba; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Cervical cancer; viral factors; visual inspection; uptake; follow up; Uganda;

    Sammanfattning : Currently 80% of cervical cancer cases worldwide arise in low income countries. In Uganda, the age standardized incidence rate of cervical cancer is estimated at 40.7 per 100,000 women. Public health policies, logistical, socio-political-cultural factors and other inequities limit the delivery of services for cervical cancer prevention. LÄS MER

  7. 10. Viral wheeze and risk factors for childhood asthma : an evaluation of clinical, immunological and genetic factors

    Författare :Katarina Stenberg Hammar; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : It’s not fully understood why some children wheeze with viral infections, and why some develop severe asthma. In this study we compared two study groups; children presenting with acute wheeze (AW) before the age of four and age-matched healthy controls (HC), and we investigated factors that might contribute to increased vulnerability for airway infections and risk of later asthma development. LÄS MER