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1. 1. The tumor suppressor gene p53 : methods for determination and their implications

   Författare :Torbjörn Norberg; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The tumor suppressor p53 plays a central part in the intracellular defense against malignant transformation and tumor progression. This, and the fact that mutations in the p53 gene are the most common genetic abnormalities so far described in human cancer, illustrates the requirement for accurate and reliable techniques for p53 status determinations. LÄS MER