Sökning: "slow progression"

Visar resultat 26 - 30 av 84 avhandlingar innehållade orden slow progression.

  1. 26. Statistical methods for early discovery of diabetic neuropathy using epidermal nerve fiber data

    Författare :Claes Andersson; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Diabetic neuropathy; Epidermal nerve fibers; Hierarchical models; Point processes; Reactive territory; Diabetic neuropathy;

    Sammanfattning : The main aim with the work in this thesis is to increase the understanding of the effects diabetic neuropathy has on the epidermal nerve fibers and thereby find methods to detect the disorder at an earlier stage. Epidermal nerve fibers (ENFs) are small sensory nerve fibers in the skin, sensing heat and pain. LÄS MER

  3. 27. Cognition in multiple sclerosis with special emphasis on MRI findings and cerebrosterol

    Författare :Gösta Bergendal; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Multiple sclerosis (MS) is a progressive inflammatory and degenerative disease of the central nervous system (CNS). This thesis focuses on cognition in MS, with special emphasis on long-term magnetic resonance imaging (MRI) findings and cerebrosterol plasma levels. LÄS MER

  4. 28. Radiological studies of LMNB1-related autosomal dominant leukodystrophy and Marinesco-Sjögren syndrome

    Författare :Johannes Finnsson; Raili Raininko; Eva Kumlien; Isabella Björkman-Burtscher; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Leukoencephalopathies; hereditary central nervous system demyelinating diseases; autonomic dysfunction; adult-onset; neuromuscular disease; pediatric; neuro-ophtalmology; ataxia;

    Sammanfattning : There are approximately 6000 to 8000 rare diseases, each with a prevalence of less than 1 / 10 000, but in aggregate affecting 6 to 8% of the population. It is important to evaluate disease development and progression to know the natural course of any disease. LÄS MER

  5. 29. Translational studies of molecular interactions in Parkinson’s disease

    Författare :Ellen Hertz; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Interactions between molecules are the basis of cellular function. In disease, these tightly regulated systems are often disturbed. Parkinson’s disease (PD) is recognized by protein aggregates in the brain of erroneously interacting molecules, directly linking the clinical picture to the molecular mechanisms. LÄS MER

  7. 30. Molecular Genetic Studies of Genes Predisposing for Glaucoma

    Författare :Mattias Jansson; Claes Wadelius; Annika Lindblom; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; glaucoma; MYOC; OCLM; GSTM1; OPTN; mutation analysis; Genetik; Clinical genetics; Klinisk genetik;

    Sammanfattning : Glaucoma is one of the leading causes of visual impairment in the world. In glaucoma, the patient’s peripheral vision is lost due to progressive and irreversible deterioration of the retinal ganglion cells and atrophy of the optic nerve. LÄS MER