Sökning: "serotonin transporter"

Visar resultat 16 - 20 av 52 avhandlingar innehållade orden serotonin transporter.

  1. 16. Molecular imaging of the serotonin system in human behaviour

    Författare :Jacqueline Borg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :positron emission tomography; serotonin; 5-HT1A receptor; 5-HTT; 5HTTÖPR; WAY100635; MADAM; cognitive functions; personality;

    Sammanfattning : The serotonin (5-HT) neurotransmission system has a role in essential physiological and psychological functions such as sleep, eating behaviour, sexuality, perception, emotion and cognition. Individual measures of serotonin biomarkers in the living human brain can be obtained using positron emission tomography (PET) imaging, direct measures of. LÄS MER

  3. 17. Study of serotonin, innervation and sensory neuropeptides in allergic contact dermatitis

    Författare :Husameldin El-Nour; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Allergic contact dermatitis; serotonin; sensory neuropeptides; nerve density;

    Sammanfattning : In a murine model of contact allergy, 24 h after challenge with antigen, increased axonal growth using an antibody to growth-associated protein-43 (GAP-43) was seen in the epidermis and dermis of eczematous skin. Protein gene product 9.5 (PGP 9.5) positive nerve fibres tended to increase in the eczematous skin. LÄS MER

  4. 18. Imaging and Quantification of Brain Serotonergic Activity using PET

    Författare :Pinelopi Lundquist; Margareta Hammarlund-Udenaes; Per Hartvig; Gunnar Blomquist; Paul Cumming; Uppsala universitet; []
    Nyckelord :Pharmacokinetics Pharmacotherapy; Brain serotonin; Neurotransmitter release; Neurotransmitter synthesis; Positron emission tomography; Tracer validation; Tracer modelling; Farmakokinetik Farmakoterapi;

    Sammanfattning : This thesis investigates the potential of using positron emission tomography (PET) to study the biosynthesis and release of serotonin (5HT) at the brain serotonergic neuron. As PET requires probe compounds with specific attributes to enable imaging and quantification of biological processes, emphasis was placed on the evaluation of these attributes. LÄS MER

  5. 19. Serotonin system in Alzheimer’s disease : from a molecular and biomarkers perspective

    Författare :Walid Tajeddinn Abderhim; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Serotonin, 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter with a wide range of biological functions. It contributes to the integrity, connectivity and function of the central nervous system (CNS). LÄS MER

  7. 20. PET studies of the serotonin system in major depression and its treatment

    Författare :Mikael Tiger; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The serotonin system has been implicated in major depression since the 1960s, mainly based on the serotonin enhancing properties of antidepressants. Positron emission tomography, PET, is the in vivo molecular imaging method with the best spatial resolution. LÄS MER