Sökning: "rif RIFIN"

Hittade 3 avhandlingar innehållade orden rif RIFIN.

  1. 1. Variant antigens at the infected red cell surface in Plasmodium falciparum malaria

    Författare :Victor Fernandez; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Plasmodium falciparum; blood stages; variant antigens; var PfEMP1; rif RIFIN; adhesive phenotypes; cytoadherence; endothelial receptor; PECAM-1 CD31; rosetting; heparan sulphate;

    Sammanfattning : Disease severity in Plasmodium falciparum infections is, to a large extent, a consequence of the parasite's efficient escape from die human host defences. Sequestration and antigenic variation are two evasion mechanisms featured by P.falciparum. LÄS MER

  3. 2. Exploration of factors that influence Plasmodium falciparum fitness and virulence

    Författare :Madle Sirel; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Malaria is an ancient disease that still has profound impact on human population. The virulence of the most lethal malaria parasite, Plasmodium falciparum, can be attributed to several features of the parasite. P. falciparum is known for its indiscriminate red blood cell (RBC) invasion and aptitude for cytoadherence. LÄS MER

  4. 3. Genomic and transcripto variation in blood stage Plasmodium falciparum

    Författare :Bobo Mok; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Antigenic variation; comparative genomic hybridization CGH ; copy number polymorphism CNP ; microarray; P. falciparum; PfEMP1; subtelomeric regions; segmental duplication; switching; var;

    Sammanfattning : Malaria research has entered a postgenomic era since October 2002, when the complete genomic sequence of Plasmodium falciparum strain 3D7 was published. A massive amount of information generated by the P. falciparum genome project has facilitated the development of many novel platforms for profiling different levels of biological aspects. LÄS MER