Sökning: "rheumatic diseases"

Visar resultat 6 - 10 av 87 avhandlingar innehållade orden rheumatic diseases.

  1. 6. Chlamydia pneumoniae in Aortic Valve Sclerosis and Thoracic Aortic Disease : Aspects of Pathogenesis and Therapy

    Författare :Christina Nyström-Rosander; Kenneth Persson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Communicable diseases; Chlamydia pneumoniae; aortic valve sclerosis; trace elements; thoracic aorta; antibiotics; Polymerase Chain Reaction PCR ; electron microscopy EM ; Infektionssjukdomar; Infectious diseases; Infektionssjukdomar; infektionssjukdomar; Infectious Diseases;

    Sammanfattning : The obligate intracellular bacterium Chlamydia pneumoniae (Cp), a common human pathogen, has been associated with atherosclerotic cardiovascular disease. The aetiology of non-rheumatic aortic valve sclerosis has, however, not been clarified. LÄS MER

  3. 7. PGE2 and other lipids in rheumatic diseases

    Författare :Joan Raouf; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Despite numerous options for treatment of rheumatic diseases, there is an unfulfilled clinical need for therapeutic strategies that can reduce inflammation and prevent tissue destruction. Lipid mediators (eicosanoids and fatty acids (FA)) are involved in the regulation of inflammatory processes and contribute to the pathogenesis of rheumatic diseases. LÄS MER

  4. 8. Pneumococcal vaccination in inflammatory rheumatic disease and in splenectomy patients. From antibody response to memory cells

    Författare :Per Nived; Reumatologi och molekylär skelettbiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pneumokockvaccin; konjugerat; Pneumokockpolysackaridvaccin; Inflammatorisk reumatisk sjukdom; Antikroppssvar; Minnesceller; Splenektomi; Pneumococcal conjugate vaccine; Pneumococcal polysaccharide vaccine; rheumatic diseases; antibody response; Splenectomy; memory cells;

    Sammanfattning : Objectives:The overall aim of the dissertation is to examine antibody response to immunization with pneumococcal vaccine in patients with inflammatory rheumatic disease (IRD), in relation to disease-modifying antirheumatic drug (DMARD) treatments, and in postsplenectomy patients.Methods:(I) Splenectomized patients without previous pneumococcal conjugate vaccine (PCV) immunization were invited to receive one dose 13-valent PCV (PCV13). LÄS MER

  5. 9. Genetic studies of the HLA locus in rheumatic diseases

    Författare :Emeli Lundström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) share a complex etiology consisting of both genetic and environmental components. Stimulation of lymphocytes and various other immune cells, release of cytokines, activation of complement and production of autoantibodies due to loss of tolerance to self-antigens, contributes to the pathogenesis of both RA and SLE. LÄS MER

  7. 10. Autoantibodies in healthy blood donors, rheumatic and autoimmune liver diseases

    Författare :Awais Ahmad; Christopher Sjöwall; Charlotte Dahle; Stergios Kechagias; Marco W.J. Schreuers; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Autoimmunity is a common phenomenon where the immune system recognises the body's own tissues. Autoimmunity can lead to disease if tissue damage occurs. Autoimmune diseases affect 5–10% of the global population and in many of these autoantibodies can be detected. The autoantibodies can be detected with several different methods. LÄS MER