Sökning: "Inflammatorisk reumatisk sjukdom"

Hittade 5 avhandlingar innehållade orden Inflammatorisk reumatisk sjukdom.

1. 1. Pneumococcal vaccination in inflammatory rheumatic disease and in splenectomy patients. From antibody response to memory cells

   Författare :Per Nived; Reumatologi och molekylär skelettbiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pneumokockvaccin; konjugerat; Pneumokockpolysackaridvaccin; Inflammatorisk reumatisk sjukdom; Antikroppssvar; Minnesceller; Splenektomi; Pneumococcal conjugate vaccine; Pneumococcal polysaccharide vaccine; rheumatic diseases; antibody response; Splenectomy; memory cells;

   Sammanfattning : Objectives:The overall aim of the dissertation is to examine antibody response to immunization with pneumococcal vaccine in patients with inflammatory rheumatic disease (IRD), in relation to disease-modifying antirheumatic drug (DMARD) treatments, and in postsplenectomy patients.Methods:(I) Splenectomized patients without previous pneumococcal conjugate vaccine (PCV) immunization were invited to receive one dose 13-valent PCV (PCV13). LÄS MER

3. 2. Collagenous colitis. Epidemiology, risk factors, clinical presentation and associated autoimmune disorders

   Författare :Lina Vigren; Gastroenterologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Autoimmunity; collagenous colitis; epidemiology; inflammatory bowel disease; lymphocytic colitis; microscopic colitis; smoking;

   Sammanfattning : Collagenous colitis (CC) affects middle-aged women and results in chronic watery non-bloody diarrhoea. The incidence of CC has increased but has never been determined in southern Sweden. During the period 2001-2010 the mean annual incidence was stable; 5.4/105 (median age 71 years). LÄS MER

4. 3. Molecular dissection of the Goodpasture epitope

   Författare :Thomas Hellmark; Njurmedicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Urologi; autoimmune; anti-GBM nephritis; glomerulonephritis; nephrology; Urology; nefrologi;

   Sammanfattning : Goodpasture disease is a prototype autoimmune disease that is characterized by a rapidly progressive glomerulonephritis, with or without lung haemorrhage, associated with autoantibodies against the glomerular basement membrane. The major antigen has previously been shown to be the non-collagenous domain of the a3 chain of type IV collagen, one of the six known a chains of type IV collagen. LÄS MER

5. 4. Tumor Necrosis Factor-alpha as a target cytokine in vascular disease

   Författare :Lena Brånén; Malmö Institutionen för kliniska vetenskaper; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; apoptosis; cell replication; Cardiovascular system; Kardiovaskulära systemet; spindle-shaped; epithelioid; smooth muscle cells; periadventitial cuff injury; sTNF-R1; bone marrow transplantation; chimeric fusion protein; atherogenic diet; ApoE; TNF-a; genetically altered mice; en face preparation; atherosclerosis; neointimal hyperplasia;

   Sammanfattning : Inflammation plays an important role in atherosclerosis. One of the most potent pro-inflammatory cytokines is tumor necrosis factor-alpha (TNF-a), a cytokine identified to have a pathogenic role in chronic inflammatory diseases such as rheumatoid arthritis (RA). LÄS MER

7. 5. Mechanisms for Targeting of Proteins to Secretory Lysosomes of Haematopoietic Cells

   Författare :Hanna Rosén; Avdelningen för hematologi och transfusionsmedicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hematologi; extracellulära vätskor; Haematology; extracellular fluids; haematopoietic cells; Medicin människa och djur ; Medicine human and vertebrates ; secretory lysosomes; protein targeting;

   Sammanfattning : The cells of the innate immune system are essential for the host's first line defence against infection. Among these cells the neutrophil granulocyte has a central role by the production of antibiotic proteins and peptides. LÄS MER