Sökning: "repeated DNA"

Visar resultat 11 - 15 av 91 avhandlingar innehållade orden repeated DNA.

  1. 11. Strategies to enhance the potency of HIV-1 DNA vaccines

    Författare :David Hallengärd; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Despite 30 years of intense research on HIV/AIDS, we have yet to arrive at a prophylactic vaccine that confers complete protection. This mission is complicated by the virus’s vast genetic variability and its ability to mask the targets for neutralizing antibodies. LÄS MER

  3. 12. Epidermal Melanocyte Response to Radiotherapy

    Författare :Per Fessé; Henrik Lindman; Ingela Turesson; Johan Ahlgren; Jan Nyman; Catharine West; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Melanocytes; fractionated radiotherapy; ΔNp63; MITF; PAX3; SOX10; p53; p21; BMI1; pRb; CXCR2; DNA-DSB; 53BP1; CXCR2;

    Sammanfattning : Cutaneous interfollicular melanocytes protect the skin from UV-radiation (UVR), and their response to UVR is well established. To date, the response activated in melanocytes by repeated genotoxic insults from radiotherapy (RT) has not been explored. LÄS MER

  4. 13. Circulating markers of risk and etiology in colorectal cancer

    Författare :Justin Harbs; Sophia Harlid; Bethany van Guelpen; Xijia Liu; Henrik Grönberg; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Colorectal cancer; CRC; sex hormones; colon cancer; DNA methylation; proteomics; risk; etiology; Cancer Epidemiology; cancerepidemiologi;

    Sammanfattning : Background: Colorectal cancer is the third most commonly diagnosed cancer in men and women. Worldwide around 2 million individuals are diagnosed each year – a number expected to increase as colorectal cancer risk factors become more prevalent. LÄS MER

  5. 14. DNA adducts formed by ethene and butadiene : quantitative analysis in rats and humans

    Författare :Chunyan Zhao; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :DNA adducts; 32P-postlabelling; cancer; genotoxicity; ethene; ethylene oxide; 1; 3-butadiene; epoxybutanediol;

    Sammanfattning : The present study has focused on DNA adduct formation by two important industrial and environmental chemicals, ethene and butadiene, in rats and humans. Ethene and butadiene are among the 50 chemicals produced in greatest volume in the United States. LÄS MER

  7. 15. Analysis of domestic dog mitochondrial DNA sequence variation for forensic investigations

    Författare :Helen Angleby; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Biotechnology; forensics; mtDNA; control region; hair; domestic dog; breed; Bioteknik; Bioengineering; Bioteknik;

    Sammanfattning : The first method for DNA analysis in forensics was presented in 1985. Since then, the introduction of the polymerase chain reaction (PCR) has rendered possible the analysis of small amounts of DNA and automated sequencing and fragment analysis techniques have facilitated the analyses. LÄS MER