Sökning: "rRNA processing"

Visar resultat 6 - 10 av 18 avhandlingar innehållade orden rRNA processing.

  1. 6. Studies on endoribonuclease RNase E and its role in RNA turnover

    Författare :Björn Sohlberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Gene regulation RNA processing mRNA stability endoribonucleases RNase E AUUUA-motifs Archaea;

    Sammanfattning : RNA turnover is an important level of regulation of gene expression, by which a cell can rapidly adjust to changes in its environment. The turnover of RNA is done by an efficient but not well understood mechanism. LÄS MER

  3. 7. Nucleolar Ribosome Assembly

    Författare :Fredrik Lackmann; Lars Wieslander; Denis Lafontaine; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Ribosome biogenesis; RNA; Nucleolus; Molecular Biology; molekylärbiologi;

    Sammanfattning : Ribosomes are macromolecular machines that are responsible for production of every protein in a living cell. Yet we do not know the details about how these machines are formed. The ribosome consists of four RNA strands and roughly 80 proteins that associate with each other in the nucleolus and form pre-ribosomal complexes. LÄS MER

  4. 8. Study of the Link between Translation Termination and Ribosome Biogenesis

    Författare :Magdalena Kaczanowska; Monica Rydén Aulin; Catherine L. Squires; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Microbiology; Mikrobiologi;

    Sammanfattning : Release factor 1 (RF1) is a ribosome-binding protein required for termination of translation in Escherichia coli. To study the effect of slow termination on protein synthesis, two isolated suppressors to a temperature sensitive (Ts) mutant allele of RF1 were studied. LÄS MER

  5. 9. Not just protein factories : role of ribosome biogenesis as an architect of epithelial-mesenchymal transition and breast cancer progression

    Författare :Varsha Prakash; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : RNA polymerase I (Pol I)-mediated transcription of ribosomal DNA (rDNA) is considered to be the rate-limiting step in ribosome biogenesis and is a well-known hallmark of cell growth and proliferation. The process of synthesizing new ribosomes is executed by the coordination of multiple complex processes in the nucleolus. LÄS MER

  7. 10. Actin and myosin in transcriptional and post-transcriptional control of gene expression

    Författare :Ales Obrdlik; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Actin plays a key role in basal gene regulation. In the past decade actin has been found to be a component of chromatin remodeling complexes, ribonucleoprotein particles and to associate with all eukaryotic RNA polymerases. LÄS MER