Sökning: "polymyositis"

Visar resultat 11 - 15 av 19 avhandlingar innehållade ordet polymyositis.

  1. 11. Immunopathogenic mechanisms in inflammatory myopathies

    Författare :Pernilla Englund; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Myositis; capillaries; muscle fibers; IL-1 alpha; MHC; adhesion molecules;

    Sammanfattning : The idiopathic inflammatory myopathies (IIMs) are characterized by symmetrical, proximal muscle weakness and by inflammatory infiltrates in muscle tissue. Based on different clinical as well as histopathological features the IlMs can be separated into polymyositis (PM), dermatomyositis (DM) and inclusion body myositis (IBM). LÄS MER

  3. 12. Physical exercise as a targeted therapy in idiopathic inflammatory myopathies

    Författare :Li Alemo Munters; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Idiopathic inflammatory myopathies are comprised of polymyositis (PM) and dermatomyositis (DM) with muscle impairment being the primary clinical feature. With the currently recommended treatment regimen, a majority of patients develop sustained impaired muscle performance and poor health for undetermined reasons. LÄS MER

  4. 13. Gene expression profiling in autoimmune diseases : a story of ups and downs

    Författare :Miranda Houtman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Autoimmune diseases are believed to arise from a combination of genetic and environmental factors that affect normal function of immune cells. In this thesis, we studied the functional role of genetic variants, in peripheral blood cells, that relate to rheumatoid arthritis (RA) and myositis by gene expression profiling. LÄS MER

  5. 14. Immunohistological studies on muscle biopsies : clinical and pathogenetic aspects on inflammatory myopathies

    Författare :Björn Lindvall; Göran Solders; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Inflammatory myopathies constitute a heterogeneous group of disorders comprising polymyositis (PM), dermatomyositis (DM), inclusion body myositis (IBM), as well as overlap syndromes where inflammatory myopathy is associated with different inflammatory systemic diseases, e.g, Sjögren's syndrome. LÄS MER

  7. 15. Mixed connective tissue disease, myositis and systemic lupus erythematosus : immunological and genetic studies in three related rheumatic autoimmune studies

    Författare :Adla Bakri Hassan; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MCTD; SLE; PM DM; autoantibodies; cytokines; MHC; polymorphisms.;

    Sammanfattning : Mixed connective tissue disease (MCTD), polymyositis (PM)/ dermatomyositis (DM) and systemic lupus erythematosus (SLE) are chronic, rheumatic, systemic inflammatory disorders. The disorders depend on several factors of both genetic and environmental origin. LÄS MER