Sökning: "polymyositis"
Visar resultat 6 - 10 av 19 avhandlingar innehållade ordet polymyositis.
6. The role of autoantibodies in inflammatory myopathies
Sammanfattning : Polymyositis (PM), dermatomyositis (DM) and inclusion body myositis (IBM), collectively called myositis, are chronic inflammatory myopathies. These disease subsets are heterogeneous but share some features, such as skeletal muscle weakness and inflammatory cell infiltrates in muscle tissue. LÄS MER
7. Experimental Chagas disease
Sammanfattning : The main focus of this thesis was to develop and utilise experimental models using the protozoan parasite Trypanosoma cruzi. We were especially interested in studying the activation of NK cells early after T. cruzi infection and what factors that predispose to a chronic inflammatory disease after T. cruzi infection. LÄS MER
8. T cell subsets and disease mechanisms in inflammatory myopathies
Sammanfattning : The idiopathic inflammatory myopathies (IIMs) are a heterogeneous group of chronic muscle disorders, typically displaying infiltrating T cells in skeletal muscle tissue and classified into polymyositis, dermatomyositis and sporadic inclusion body myositis. Several studies involving both humans and animal models point towards a role for T cells in the pathogenesis of IIMs, however, the precise phenotype, functionality and specificity of pathogenic T cells remain elusive. LÄS MER
9. The Clinical and Pathological Spectrum of Idiopathic Inflammatory Myopathies : Implications for pathogenesis, classification and diagnosis
Sammanfattning : Background: Idiopathic inflammatory myopathies (IIM) constitute a heterogeneous group of diseases with severe consequences for the life of affected patients. Dermatomyositis, polymyositis and inclusion body myositis (IBM) are the classical representatives of this group. LÄS MER
10. Autoantibodies and the type I interferon system in idiopathic inflammatory myopathies
Sammanfattning : Idiopathic inflammatory myopathies (IIM), also known as myositis, are rare autoimmune diseases, characterized by proximal muscle weakness and inflammatory cells in skeletal muscle tissue. The most common subgroups are polymyositis (PM), dermatomyositis (DM) and inclusion body myositis (IBM). LÄS MER