Sökning: "PM DM"

Visar resultat 1 - 5 av 15 avhandlingar innehållade orden PM DM.

  1. 1. Mixed connective tissue disease, myositis and systemic lupus erythematosus : immunological and genetic studies in three related rheumatic autoimmune studies

    Författare :Adla Bakri Hassan; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MCTD; SLE; PM DM; autoantibodies; cytokines; MHC; polymorphisms.;

    Sammanfattning : Mixed connective tissue disease (MCTD), polymyositis (PM)/ dermatomyositis (DM) and systemic lupus erythematosus (SLE) are chronic, rheumatic, systemic inflammatory disorders. The disorders depend on several factors of both genetic and environmental origin. LÄS MER

  3. 2. Hand function, activity limitation and health-related quality of life in patients with polymyositis and dermatomyositis

    Författare :Malin Regardt; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Polymyositis (PM) and dermatomyositis (DM) are rare idiopathic inflammatory myopathies. Common clinical features are proximal muscle weakness and reduced muscle endurance, which can lead to activity limitation and reduced health-related quality of life (HRQoL). LÄS MER

  4. 3. Physical exercise as a targeted therapy in idiopathic inflammatory myopathies

    Författare :Li Alemo Munters; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Idiopathic inflammatory myopathies are comprised of polymyositis (PM) and dermatomyositis (DM) with muscle impairment being the primary clinical feature. With the currently recommended treatment regimen, a majority of patients develop sustained impaired muscle performance and poor health for undetermined reasons. LÄS MER

  5. 4. Exercise and outcome measures in patients with polymyositis and dermatomyositis

    Författare :Helene Alexanderson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Inflammatory myopathies; exercise; outcome measures; disability;

    Sammanfattning : Polymyositis (PM) and dermatomyositis (DM) are chronic idiopathic inflammatory myopathies (IIM) which are clinically characterized by symmetrical proximal muscle weakness, fatigue, myalgia and extra- muscular involvement. Muscle impairment is the most significant feature of PM and DM with characteristic infiltrates of mononuclear inflammatory cells in muscle biopsies, elevated inflammatory parameters in serum and characteristic EMG changes, which separate these disorders from neurologic disorders and also fibromyalgia. LÄS MER

  7. 5. Immune mechanisms in chronic rheumatic muscle inflammation, myositis

    Författare :Quan Tang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The idiopathic inflammatory myopathies (IIM), shortly named myositis, is a group of heterogeneous and rare autoimmune diseases with the target tissue of skeletal muscle. It is not curable and affects the daily life of patients. The treatment of myositis is mainly glucocorticoids in combination with immunosuppressive agents. LÄS MER