Sökning: "platelet recruitment"

Visar resultat 6 - 10 av 38 avhandlingar innehållade orden platelet recruitment.

  1. 6. Pericyte recruitment and functions in vivo. Studies of platelet-derived growth factor-B deficient embryos

    Författare :Mats Hellström; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mouse; gene targeting; platelet-derived growth factor; pericyte; vascular smooth muscle; angiogenesis;

    Sammanfattning : A functional vascular system is essential for tissue growth and maintenance, and the circulatory system is therefore the first operational organ of the vertebrate embryo. In conditions of pathological tissue growth, such as tumors, formation of new blood vessels is also required, and it is anticipated that prevention of blood vessel development in those settings might ameliorate the disease progress. LÄS MER

  2. 7. Tumor angiogenesis. Regulation of mural cell recruitment and endothelial sprouting

    Författare :Alexandra Abramsson; Göteborgs universitet; []
    Nyckelord :Angiogenesis; tumor; retina; PDGF; VEGF; platelet-derived growth factor; guidance; vascular endothelial growth factor.;

    Sammanfattning : The formation of new blood vessels is an inherent part of many physiological and pathological processes. Currently, there is a strong hope pathological situations like stroke, diabetic retinopathy and cancer may be affected by pharmacological regulators of blood vessel formation. LÄS MER

  3. 8. On Leukocyte Recruitment in Cholestatic Liver Injury

    Författare :Matthias Laschke; Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Leukocyte and Liver; Inflammation; Cholestasis; Endothelium;

    Sammanfattning : Cholestasis is a frequent clinical syndrome, which is caused by a dysfunction in bile formation of the hepatocyte or from obstruction of the biliary tract. This is associated with inflammation of the liver tissue, resulting in severe liver injury. In this inflammatory process, leukocyte recruitment has emerged as a key feature. LÄS MER

  4. 9. Platelet-lymphocyte cross-talk in atherogenesis : experimental studies on platelet-regulated lymphocyte adhesion and CD4+ T cell activation

    Författare :Zhu Linjing; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Atherosclerosis is an inflammatory and thrombotic disease. Platelets and lymphocytes, especially CD4+ T cells, are indispensable players during the initiation and progression of atherosclerotic lesion formation. During the early stage of atherogenesis, lymphocytes are generally thought to be recruited from arterial blood flow. LÄS MER

  5. 10. On Microvascular Inflammation and Intestinal Leakage in Radiation Enteropathy

    Författare :Andrada Röme; Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; radiation; colon; intestinal leakage; Leukocyte and platelet recruitment;

    Sammanfattning : Gastrointestinal tract damage is an insidious feature in patients undergoing radiotherapy. Microvascular inflammation, including leukocyte and platelet recruitment as well as epithelial barrier dysfunction, are considered to constitute key components in the pathophysiology of radiation-induced enteropathy. LÄS MER