Sökning: "platelet recruitment"

Visar resultat 11 - 15 av 38 avhandlingar innehållade orden platelet recruitment.

  1. 11. On Neutrophil and Platelet Adhesive Interactions in Septic Lung Injury

    Författare :Asad Muhammad; Kirurgi; []
    Nyckelord :Leukocytes; chemokines; platelets; lung; sepsis;

    Sammanfattning : Sepsis induced by intestinal perforation is a life-threatening illness and is a frequent cause of leukocyte-mediated lung injury. Although antimicrobial therapy has been the central clinical strategy for these patients, the survival rates in such patients are still very low because of their impaired host defense mechanisms. LÄS MER

  3. 12. Role of platelet-derived growth factor B in cholesterol and glucose metabolism

    Författare :Tian Li; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Platelet-derived growth factor (PDGFB) is a critical molecule for recruiting pericytes. Due to the fundamental role of the pericytes in angiogenesis and vascular stability, PDGFB knockout mice die perinatally from severe hemorrhage and edema. LÄS MER

  4. 13. Biological activities of novel platelet-derived growth factors, PDGF-C and PDGF-D

    Författare :Annica Pontén; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Platelet-derived growth factors (PDGFs) belong to the PDGF/VEGF (vascular endothelial growth factor) family of growth factors. Members of this family share a common structural feature, a conserved PDGF/VEGF homology domain, containing eight invariant cysteine residues. LÄS MER

  5. 14. Transcriptional Regulation of the Platelet-Derived Growth Factor B-receptor by p53 Family Members

    Författare :Daniel Wetterskog; Göteborgs universitet; []
    Nyckelord :;

    Sammanfattning : Aims: The platelet-derived growth factor ?-receptor (PDGFRB) is critically involved in embryonic development and has a role in many diseases. In cells, signaling through PDGFRB affects growth, migration and death. LÄS MER

  7. 15. Role of extracellular retention of platelet-derived growth factor-B. Functions in development and disease

    Författare :Per Lindblom; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PDGF; pericyte; cancer; fibrosis; ECM; HSPG; cell retention; endothelial;

    Sammanfattning : During development, the cell secretes growth and differentiation factors (GDFs) to the surrounding microenvironment. These factors are often key regulators of organogenesis and embryogenesis. Several GDFs carry sequences that mediate specific interaction with molecules of the extracellular matrix (ECM) that surrounds the cell. LÄS MER