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Visar resultat 1 - 5 av 38 avhandlingar som matchar ovanstående sökkriterier.
1. Platelet-dependent pulmonary recruitment of neutrophils in abdominal sepsis
Sammanfattning : Sepsis and subsequent multiple organ failure remain the major cause of mortality in intensive care units. Leukocyte-mediated tissue damage is a key feature in septic lung injury. Accumulating data suggest that platelets play a role in inflammation and tissue injury. LÄS MER
2. Rac1 signaling regulates platelet-dependent inflammation abdominal sepsis
Sammanfattning : Sepsis is a systemic inflammatory response syndrome to a localized or systemic infection that leads to the over production of proinflammatory cytokines and the ultimate failure of multiple organ systems. However, little is known about the potential role of Rac1 in controlling sepsis-induced intracellular signaling pathways. LÄS MER
3. Microcirculation, Mucus and Microbiota in Inflammatory Bowel Disease
Sammanfattning : Inflammatory bowel diseases, (IBD), are a group of chronic disorders of the gastro-intestinal tract, and include Crohn’s disease (CD) and Ulcerative Colitis (UC). The pathogenesis is not known, but involves at least in part a loss of tolerance towards the commensal colonic microbiota. LÄS MER
4. Organ-specific mechanisms of vascular development in the mesentery
Sammanfattning : Understanding how the vascular systems are formed has significant clinical importance. General mechanisms underlying vascular development have been extensively studied during the past decades. However, the mechanisms regulating the development and function of the blood and lymphatic vessels in specific organs are poorly understood. LÄS MER
5. Innate immune cell response in sepsis
Sammanfattning : Leukocyte recruitment is known to be a key feature at sites of inflammation and important in the combat against infectious agents. However, the mechanisms of leukocyte recruitment in the pulmonary microvasculature in response to local and systemic inflammation remain elusive. LÄS MER