Sökning: "picolinic acid"

Hittade 3 avhandlingar innehållade orden picolinic acid.

  1. 1. Vanadate and Peroxovanadate Complexes of Biomedical Relevance : A speciation approach with focus on diabetes

    Författare :András Gorzsás; Lage Pettersson; Carlos F. G. C. Geraldes; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Inorganic chemistry; vanadium; hydrogen peroxide; lactate; citrate; phosphate; alanyl serine; picolinic acid; speciation; formation constants; equilibrium; solution structure; potentiometry; NMR 51V; 31P; 13C; 1H ; Oorganisk kemi; Inorganic chemistry; Oorganisk kemi; oorganisk kemi; Inorganic Chemistry;

    Sammanfattning : Diabetes mellitus is one of the most threatening epidemics of modern times with rapidly increasing incidence. Vanadium and peroxovanadium compounds have been shown to exert insulin–like actions and, in contrast to insulin, are orally applicable. However, problems with side–effects and toxicity remain. LÄS MER

  3. 2. Lifestyle, biomarkers and the risk of developing inflammatory bowel disease

    Författare :Lovisa Widbom; Johan Hultdin; Pontus Karling; Kim Ekblom; Kristina Stefansson; Andreas Münch; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Inflammatory bowel disease; ulcerative colitis; Crohn s disease; smoking; cotinine; iron deficiency; ferritin; pyridoxal-5-phosphate; kynurenine pathway; Clinical Chemistry; klinisk kemi; invärtesmedicin; Internal Medicine;

    Sammanfattning : Introduction: Inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn’s disease (CD), is a chronic disease causing inflammation in the gut mucosa. The pathogenesis involves alteration in gut microbiota and in the intestinal barrier due to genetic factors, environmental exposure and dysregulation of the immune response. LÄS MER

  4. 3. The kynurenine pathway in body and brain : relation with physical exercise and mental health

    Författare :Ada Trepci; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The kynurenine pathway of tryptophan degradation is the focus in a variety of research fields and several of the metabolites produced along the pathway are suggested as future biomarkers. Growing interest in a better understanding of the physiological and the pathophysiological importance of kynurenine pathway metabolites is followed by the need for a robust, sensitive method that can quantify multiple metabolites simultaneously. LÄS MER