Sökning: "pharmacokinetics skin"

Visar resultat 11 - 12 av 12 avhandlingar innehållade orden pharmacokinetics skin.

  1. 11. Acute intermittent porphyria : studies of chronic disease, recombinant enzyme therapy and late complications

    Författare :Eliane Sardh; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Acute intermittent porphria; porphobilinogen; 5-aminolevulinic acid; porphobilinogen deaminase; enzyme therapy; acute porphyria attack; chronic active disease; late complications;

    Sammanfattning : This thesis comprise five studies on patients with acute intermittent porphyria (AIP) observed under different clinical conditions associated with the disorder. They have generally been monitored at the porphyria out-patient clinic in Stockholm South Hospital, and were biochemically monitored at Porphyria Centre Sweden. LÄS MER

  2. 12. Tracer development and PET studies : labeled proinsulin C-peptide and an EGFR-TK inhibitor

    Författare :Anna Fredriksson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :PET; imaging; kinetics; oncology; EGFR; PD153035; diabetes; C-peptide;

    Sammanfattning : Positron emission tomography (PET), which localizes and quantifies positron decays over time, enables non-invasive in vivo distribution studies of trace amounts of compounds labeled with positron emitters. The use of PET to image disease processes is growing as the number of available tracers increases and, especially, as they become more selective and specific. LÄS MER