Sökning: "pharmaceutical mixtures"

Visar resultat 31 - 33 av 33 avhandlingar innehållade orden pharmaceutical mixtures.

  1. 31. Asymmetric Hydrogenations : Syntheses of Ligands and Expansion of Substrate Scope

    Författare :Pradeep Cheruku; Pher Andesson; Jay Siegel; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Catalysis; Asymmetric; Hydrogenations; Reductions; Olefins; Imines; Enol phosphinates; Transition metal; Complexes; Iridium; Enamines; Ruthenium; Ligands; Trifluoromethyl; Diphenylvinylphosphine oxides; Vinyl phosphonates; Chemistry; Kemi;

    Sammanfattning : Asymmetric hydrogenation has emerged as a versatile methodology to obtain a wide range of chiral precursors. This thesis focused on the synthesis of new chiral ligands and the expansion of the substrate scope of asymmetric hydrogenations. LÄS MER

  3. 32. Mechanisms of adhesive mixing for drug particle inhalation (Numerical investigation of the interplay between formulation variables)

    Författare :Mohammadreza Tamadondar; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Discrete Element Method; Agglomerate; Carrier Particle; Adhesive mixing; Dispersion; DPI-formulation;

    Sammanfattning : Formulation of therapeutic dry powders for lung drug delivery via inhalation is done via adhesive mixing. In this process, micron-sized active pharmaceutical ingredient particles are blended with relatively coarse carrier particles until stable adhesive units of carrier and drug particles are formed. LÄS MER

  4. 33. Application of the benchmark dose-response modelling approach for risk characterization of chemicals

    Författare :Antero Vieira da Silva; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Toxicology is the discipline that investigates the possible adverse effects of chemical exposure on human, animal and environmental health. Chemical risk assessment is the process that aims to identify potentially hazardous substances and describes the probability of adverse outcomes associated with their exposure. LÄS MER