Sökning: "pharmaceutical mixtures"

Visar resultat 21 - 25 av 33 avhandlingar innehållade orden pharmaceutical mixtures.

1. 21. Effect of water on the glass transition and properties of solid-state pharmaceutical formulations

   Författare :Ekaterina Bogdanova; Vitaly Kocherbitov; Thomas Rades; Malmö universitet; []
   Nyckelord :glass transition; glass transition temperature; relaxation; sucrose; trehalose; maltodextrin; lysozyme; unfolding; hydration; solid-stae; sorption calorimetry; Health and society; Hälsa och samhälle;

   Sammanfattning : The aim of this thesis was to increase our knowledge of the glassy state and the glass transition phenomenon and to evaluate the effect of water on the glassy state. To accomplish this, investigations were focused on the amorphous sucrose-water (paper I, II, III), trehalose-water (paper I), maltodextrin-water (paper I), and lysozyme-sucrose-water (paper IV) systems. LÄS MER

3. 22. Characterisation of Aqueous Solutions, Liquid Crystals and Solid State of Non-ionic Polymers in Association with Amphiphiles and Drugs

   Författare :Annika Ridell; Martin Malmsten; Sven Engström; David Attwood; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Physical chemistry; polymer; surfactant; phase diagram; x-ray diffraction; fluorescence spectroscopy; calorimetry; PEG; cellulose ether; viscometry; cubic phase; liquid crystals; drugs; solid dispersion; Fysikalisk kemi; Physical chemistry; Fysikalisk kemi; Fysikalisk och oorganisk farmaceutisk kemi; Physical and Inorganic Pharmaceutical Chemistry;

   Sammanfattning : Cellulose ethers and polyethylene glycols are used in drug formulations as water swelling or water soluble matrices. Polar lipids, for example monoglycerides, and surfactants can be used to solubilise hydrophobic or amphiphilic drugs and to formulate potential drug delivery vehicles such as emulsions, liposomes and cubic phases. LÄS MER

4. 23. Drug Diffusion and Nano Excipient Formation Studied by Electrodynamic Methods

   Författare :Ulrika Brohede; Maria Strømme; Göran Frenning; Hans Leuenberger; Uppsala universitet; []
   Nyckelord :Functional materials; drug release; electrodynamic methods; diffusion; Funktionella material;

   Sammanfattning : New smart drugs demand new smart drug delivery systems and also new smart analysis methods for the drug delivery process and material characterization. This thesis contributes to the field by introducing a new electrodynamic approach for studying the drug diffusion proc-esses as well as the formation of a new type of drug delivery systems, the so called mesoporous nano excipients. LÄS MER

5. 24. Investigating polymorphism in small molecules using three-dimensional electron diffraction

   Författare :Molly Lightowler; Xiaodong Zou; Hosea M. Nelson; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; 3D electron diffraction; structure determination; polymorphism; crystallisation; phase identification; small molecule; oorganisk kemi; Inorganic Chemistry;

   Sammanfattning : For scientific, regulatory and intellectual property reasons, the discovery and characterisation of polymorphic systems is an integral aspect of the development process of any solid-formulated drug product. Yet, these studies are often hindered by crystal quality and size, poor yields and the generation of mixtures of phases. LÄS MER

7. 25. Resonant Microwave Sensors for Industrial Applications

   Författare :Johan Nohlert; Chalmers tekniska högskola; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; finite element method; eigenvalue problems; microwave resonances; parameter estimation; process monitoring; microwave measurements; detection;

   Sammanfattning : This thesis presents developments in the area of microwave-based sensor systems for industrial applications. The work is motivated by a need for advanced measurement techniques in industry in general, and the process industry in particular. LÄS MER