Sökning: "pathogenesis immunoregulation"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden pathogenesis immunoregulation.

  1. 1. Interplay between Pathogenic and Immune Regulatory Mechanisms in G-alpha-i2 deficient colitis

    Författare :Yu-Yuan Chiu Götlind; Göteborgs universitet; []
    Nyckelord :IBD; G-alpha-i2 colitis; Tregs; Teffs; Th17 Th1; pathogenesis immunoregulation;

    Sammanfattning : The two major forms of inflammatory bowel disease (IBD), Crohn's disease (CD) and ulcerative colitis (UC) are gastrointestinal disorders characterized by chronic and relapsing inflammation. Mice deficient in the inhibitory G protein subunit Gαi2 spontaneously develop chronic colitis and have been used as a model for IBD, with particular similarities to UC. LÄS MER

  3. 2. Immunoregulation in experimental autoimmune myasthenia gravis

    Författare :Hua-Bing Wang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Myasthenia gravis (MG) derives its name from Latin and Greek words meaning, "grave muscle weakness". MG is a classical T cell dependent antibody-mediated autoimmune disease. LÄS MER

  4. 3. Immunoregulation and immunotherapy in experimental autoimmune neuritis

    Författare :Li-Ping Zou; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Experimental autoimmune neuritis (EAN) is a CD4+ T cell mediated autoimmune disease of the peripheral nervous system (PNS). EAN represents an animal model for studying the immunopathogenesis and immunotherapy of Guillain-Barré syndrome (GBS). LÄS MER

  5. 4. Immunoregulation of experimental autoimmune neurirtis focuses on cell immunity

    Författare :Yu Zhu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Experimental autoimmune neuritis (EAN) is a CD4+ T cell mediated autoimmune disease of peripheral nervous system (PNS). EAN can be induced in susceptible animal strains by active immunization with peripheral nerve tissue, the purified peripheral nerve myelin components P2 and PO, or synthetic P2 and PO peptides. LÄS MER

  7. 5. Immunoregulation and immunogenetics of monophasic and relapsing experimental autoimmune encephalomyelitis with emphasis on cytokines

    Författare :Shohreh Issazadeh; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Experimental autoimmune encephalomyelitis (EAE) is a CD4+ T cell mediated autoimmune disease of the central nervous system (CNS) that resembles multiple sclerosis (MS). An MS-like histopathology and disease course can be provoked by immunization of susceptible animals with inoculum containing CNS antigens. LÄS MER