Avancerad sökning

Hittade 4 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Autoimmunogenetic Aspects of Vaccine-induced Narcolepsy. As part of the AMINA - Autoimmune Multiple Sclerosis and Narcolepsy Study

    Författare :Alexander Lind; Pediatrisk endokrinologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Narcolepsy type 1 (NT1) is a neurological sleep disorder. The biological cause is the degeneration of hypocretin neurons located in the hypothalamus. It has been suggested that NT1 has an autoimmune pathogenesis, as in most patients, the Human Leukocyte Antigen (HLA)-DQB1*06:02:01 is present. LÄS MER

  3. 2. Influenza specific T- and B-cell responses in immunosuppressed patients

    Författare :Aditya Sai Ambati; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Influenza, known as the ‘flu’, is a recurrent acute viral infection that might cause severe inflammation, particularly in vulnerable individuals, i.e. young children, the elderly, and immune-suppressed patients, such as stem cell transplant recipients. LÄS MER

  4. 3. Vaccine safety, vaccine effectiveness and other determinants for successful immunisation programmes

    Författare :Favelle Lamb; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The studies in this thesis examined several key determinants for successful uptake of vaccinations in the Nordic countries, with focus on vaccine safety and vaccine effectiveness. In study I, we investigated whether disease history is a risk factor for narcolepsy after vaccination with the pandemic influenza vaccine, Pandemrix, which was circulated between 2009 and 2010. LÄS MER

  5. 4. Narcolepsy in children: Relationship to the H1N1 influenza vaccination, association with psychiatric and cognitive impairments and consequences in daily life

    Författare :Attila Szakacs; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; narcolepsy; incidence; children; psychiatric comorbidity; cognition; adaptive behavior; quality of life; parenting stress;

    Sammanfattning : Background/aims: Narcolepsy is a lifelong sleep disorder with an onset most frequently in the second decade of life. The cardinal symptoms are excessive daytime sleepiness, cataplexy, hypnagogic and hypnopompic hallucinations sleep paralysis and disturbed nighttime sleep. LÄS MER