Sökning: "oral anticoagulants"

Visar resultat 11 - 15 av 34 avhandlingar innehållade orden oral anticoagulants.

  1. 11. On Acute Mesenteric Venous Thrombosis

    Författare :Saman Salim; Vaskulära sjukdomar - kliniska studier; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mesenteric venous thrombosis; intestinal ischemia; Venous thromboembolism; Thrombophilia; Anticoagulation; Direct oral anticoagulants; Vitamin K antagonists;

    Sammanfattning : .... LÄS MER

  2. 12. Antithrombotic treatment of atrial fibrillation before and after the introduction of non-vitamin K antagonist oral anticoagulants (NOAC) in the Stockholm health care region

    Författare :Tomas Forslund; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Atrial fibrillation (AF) is the most common cardiac arrhythmia and the major risk factor for thromboembolic stroke. Effective treatment with the oral anticoagulant (OAC) warfarin has been available for decades. However warfarin treatment is complicated, and demands dose adjustments and regular monitoring. LÄS MER

  3. 13. The in-vitro and in-vivo metabolism of the oral anticoagulant phenprocoumon as influenced by genetic polymorphisms of cytochrome P4502C9

    Författare :Mike Ufer; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Drug metabolism; cytochrome P450; genetic polymorphism; genotyping; CYP2C9; phenprocoumon; warfarin; acenocoumarol; oral anticoagulants;

    Sammanfattning : Oral anticoagulants are widely used for the prevention of thromboembolic disorders. Warfarin (WA) is most commonly used world-wide, while phenprocoumon (PPC) is the first-line anticoagulant in some European countries including Germany. Each anticoagulant exists in two different enantiomeric forms and is administered orally as a racemate. LÄS MER

  4. 14. Effects of direct oral anticoagulant treatment on hemostasis in patients with atrial fibrillation

    Författare :Viktor Schutz Taune; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The direct oral anticoagulants (DOAC) – dabigatran, rivaroxaban, apixaban and edoxaban – were approved without the need for routine monitoring. However, in parallel with clinical implementation, studies on how to measure the effect of DOACs have become a research area of increasing interest during the last decade. LÄS MER

  5. 15. Oral anticoagulation treatment in atrial fibrillation - To bleed or not to bleed, that is the question

    Författare :Mattias Wieloch; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; anticoagulation; atrial fibrillation; hemorrhage; kidney; warfarin; epidemiology; stroke;

    Sammanfattning : Background: Oral antigoagulation treatment (OAT) with warfarin have a narrow therapeutic window and patients exhibit a highly variable doseresponse that is attributable to genetic, disease-related,and environmental factors as well as prescription and nonprescription drugs, dietary vitamin K and alcohol. The effect of warfarin treatement on blood coagulation is measured using international normalized ratio (INR). LÄS MER