Sökning: "membrane protein topology"

Visar resultat 26 - 30 av 58 avhandlingar innehållade orden membrane protein topology.

  1. 26. NADH:quinone oxidoreductase: the black box of the respiratory chain

    Författare :Robert Roth; Biokemi och Strukturbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NADH:quinone oxidoreductase; Complex I; electron transport; membrane protein; ubiquinone; respiratory chain; respiration; metabolism; Metabolism; Biokemi; Biochemistry;

    Sammanfattning : Complex I or NADH:quinone oxidoreductase the largest, most complex and least understood of the five membrane-bound enzyme complexes constituting the mitochondrial respiratory chain. The enzyme is present in all types of organisms, from bacteria to mammals. LÄS MER

  3. 27. On the antiporter-like subunits of respiratory chain Complex I - implications for the evolution and coupling mechanism of the NADH:quinone oxidoreductase enzyme complex

    Författare :Cecilie Mathiesen; Biokemi och Strukturbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Metabolism; Biokemi; metabolism; Biochemistry; mrp; electron transport; respiration; membrane protein;

    Sammanfattning : Complex I or NADH:quinone oxidoreductase is the largest enzyme complex, but the least understood energy coupling site in the respiratory chain of mitochondria and bacteria. No high-resolution structural information exists for this enzyme and the molecular mechanism that couples electron transfer and proton pumping is not understood. LÄS MER

  4. 28. Structure, Mechanism, and Regulation of Sodium/Proton Exchangers

    Författare :Iven Winkelmann; Drew David; Rajini Rao; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; sodium proton exchange; SLC9; structure; secondary active transport; membrane protein; Biochemistry; biokemi;

    Sammanfattning : Sodium/proton exchangers (NHEs) are secondary active transporters that are ubiquitously found in all kingdoms of life. They facilitate the exchange of protons for sodium ions or other inorganic ions across biological membranes, regulating pH, sodium levels, and osmotic pressure. LÄS MER

  5. 29. Glypican-1: Structural and functional analysis of the N-glycosylated human protein

    Författare :Wael Awad Abdelhady; Biokemi och Strukturbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Proteoglycans; glypicans; glypican-1; heparan sulphate; N-glycosylation; exostosin-proteins; X-ray crystallography; crystal dehydration; diffraction anisotropy; Small angle X-ray scattering SAXS9; protein spectroscopy;

    Sammanfattning : Glypicans are multifunctional cell surface heparan sulphate proteoglycans co-regulating numerous signalling pathways, and are thereby involved in the control of cellular division, differentiation, and morphogenesis. The heparan sulphate (HS) chains are responsible for many of those biological functions; nevertheless recent studies suggest functional roles for the glypican core proteins in mediating the signalling of various growth factors. LÄS MER

  7. 30. Predicting transmembrane topology and signal peptides with hidden Markov models

    Författare :Lukas Käll; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Membrane protein; signal peptide; hidden Markov model; bioinformatics;

    Sammanfattning : Transmembrane proteins make up a large and important class of proteins. About 20% of all genes encode transmembrane proteins. They control both substances and information going in and out of a cell. LÄS MER