Sökning: "melanocytes"

Visar resultat 21 - 25 av 36 avhandlingar innehållade ordet melanocytes.

  1. 21. Functional Studies of Genes Associated with Muscle Growth in Pigs and Hair Greying in Horses

    Författare :Lin Jiang; Leif Andersson; Kerstin Lindblad-Toh; Gerli Pielberg; Christopher Tuggle; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; QTN; muscle development; IGF2; ZBED6; RNA-seq; ChIP-seq; myoblasts; pancreatic beta cells; Grey horse; melanoma; MITF; Biologi med inriktning mot molekylär cellbiologi; Biology with specialization in Molecular Cell Biology;

    Sammanfattning : Domestic animals have become very different from their wild ancestors during domestication and animal breeding. This provides a good model to unravel the molecular mechanisms underlying phenotypic variation. In my thesis I have studied genes affecting two important traits, leanness in pigs and hair greying-associated melanoma in horses. LÄS MER

  3. 22. Fibroblast Differentiation and Models of Human Skin

    Författare :Jonathan Rakar; Gunnar Kratz; Ingemar Rundquist; Anders Lindahl; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : This thesis combines three publications and one manuscript, covering two principal topics: functional differentiation of human fibroblasts and laboratory models of human skin. The two topics favourably unite in the realm of tissue engineering. This thesis is therefore split into three main parts: 1. LÄS MER

  4. 23. Cutaneous effects of nerve injury : An experimental study in the rat

    Författare :Nenad Stankovics; Göran Lundborg; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : One of the most difficult tasks of the hand surgeon is to reach a satisfactory restoration of the nerve functions of the injuried hand. In spite of the use of meticulous microsurgery, the results of nerve repair are disappointing, particularly with respect to mixed nerve trunks. LÄS MER

  5. 24. Clinical and functional aspects of microRNA regulation in human cancers

    Författare :Stefano Caramuta; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : miRNAs are short single-stranded non-coding RNAs which regulate gene expression at the post-transcriptional level in many biological processes, including proliferation, apoptosis and differentiation. A number of studies have shown the importance of miRNAs in carcinogenesis and accumulating evidence supports their role as diagnostic and prognostic biomarkers in human cancers. LÄS MER

  7. 25. Molecular genetics of cutaneous malignant melanoma

    Författare :Malihe Eskandarpour; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cutaneous malignant melanoma is an aggressive tumor of melanocytes in the skin with rapidly increasing incidence. Patients with advanced disease have a poor prognosis since the tumor is usually resistant to current therapies. Therefore, the development of novel strategies for preventing and treating melanoma is important. LÄS MER