Sökning: "medium spiny projection neurons"

Visar resultat 1 - 5 av 7 avhandlingar innehållade orden medium spiny projection neurons.

1. 1. Computer Modelling of Neuronal Interactions in the Striatum

   Författare :Johannes Hjorth; Jeanette Hellgren Kotaleski; Kevin Gurney; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; striatum; fast spiking interneurons; medium spiny projection neurons; gap junctions; interoperability; MUSIC; Computer science; Datavetenskap;

   Sammanfattning : Large parts of the cortex and the thalamus project into the striatum,which serves as the input stage of the basal ganglia. Information isintegrated in the striatal neural network and then passed on, via themedium spiny (MS) projection neurons, to the output stages of thebasal ganglia. LÄS MER

3. 2. Modeling receptor induced signaling in MSNs : Interaction between molecules involved in striatal synaptic plasticity

   Författare :Anu G. Nair; Jeanette Hellgren Kotaleski; Omar Gutierrez-Arenas; Upinder S. Bhalla; Pierre Vincent; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Striatal synaptic plasticity; LTP; Dopamine; Acetylcholine; Synergy; Medium spiny neurons; MSNs;

   Sammanfattning : Basal Ganglia are evolutionarily conserved brain nuclei involved in several physiologically important animal behaviors like motor control and reward learning. Striatum, which is the input nuclei of basal ganglia, integrates inputs from several neurons, like cortical and thalamic glutamatergic input and local GABAergic inputs. LÄS MER

4. 3. Information processing in the Striatum : a computational study

   Författare :Johannes Hjorth; Jeanette Hellgren Kotaleski; Anders Lansner; Kim Blackwell; KTH; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; striatum; fast spiking interneuron; gap junctions; synchronisation; up-state detection; CaMKII; mathematical modelling; Neuroscience; Neurovetenskap;

   Sammanfattning : The basal ganglia form an important structure centrally placed in the brain. They receive input from motor, associative and limbic areas, and produce output mainly to the thalamus and the brain stem. The basal ganglia have been implied in cognitive and motor functions. LÄS MER

5. 4. Cellular and synaptic properties in the lamprey striatum

   Författare :Jesper Ericsson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The striatum is the main input structure of the basal ganglia, a group of subcortical nuclei that are central to the control of different patterns of motor behaviours and for the selection of actions, a fundamental problem facing all animals. The main focus of this thesis has been to characterize the cellular and synaptic mechanisms of the striatum and its relation to other basal ganglia nuclei in the lamprey. LÄS MER

7. 5. The role of striatal inhibition in the processing of cortical neuronal avalanches

   Författare :Andreas Klaus; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The brain is spontaneously active even in the absence of any obvious motor actions or sensory perceptions. This so-called resting activity or ongoing activity reflects the myriads of neuronal interactions necessary for the brain to process past actions, allow for current inputs, and prepare for future decisions and responses. LÄS MER