Sökning: "medical experiments"

Visar resultat 21 - 25 av 701 avhandlingar innehållade orden medical experiments.

  1. 21. Fibroblast Differentiation and Models of Human Skin

    Författare :Jonathan Rakar; Gunnar Kratz; Ingemar Rundquist; Anders Lindahl; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : This thesis combines three publications and one manuscript, covering two principal topics: functional differentiation of human fibroblasts and laboratory models of human skin. The two topics favourably unite in the realm of tissue engineering. This thesis is therefore split into three main parts: 1. LÄS MER

  2. 22. Translating Cardiac and Cardiometabolic GWAS Using Zebrafish

    Författare :Benedikt von der Heyde; Marcel den Hoed; Anastasia Emmanouilidou; Erik Ingelsson; Shawn Burgess; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; GWAS; Zebrafish; Medicinsk genetik; Medical Genetics;

    Sammanfattning : Genome-wide association studies (GWAS) have identified thousands of loci associated with cardiac and cardiometabolic traits. However, the trait-associated variants usually do not clearly point to causal gene(s), mechanism(s) or tissue(s). Model systems that allow for a comprehensive and quick candidate gene screening are necessary, ideally in vivo. LÄS MER

  3. 23. Radiobiological investigations of proton and light ion therapy

    Författare :Nina Tilly; Michael Scholz; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Radiobiology; Monte Carlo method; Radiotherapy; high-energy instrumentation; Protons; Light ions; RBE; LET; Radiobiological models; Radiobiologi; medicinsk strålningsfysik; Medical Radiation Physics;

    Sammanfattning : During the last decade, the interest in proton and light ion beam therapy has increased considerably and several new centres are planned around the world. These particles have a large advantage due to their sharp physical dose distributions as compared to conventional radiotherapy beams. LÄS MER

  4. 24. Investigation of potential prognostic and therapeutic genes in pathologic neovascularization of the retina

    Författare :Parviz Mammadzada; Karolinska Institutet; Karolinska Institutet; Sweden Stockholm Karolinska Institutet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Pathologic angiogenesis of the retina is a hallmark of frequent blinding conditions among the elderly, such as proliferative diabetic retinopathy (PDR) and neovascular age-related macular degeneration (nAMD). The underlying mechanisms are complex. LÄS MER

  5. 25. Molecular mechanisms mediating development of pulmonary cachexia in COPD

    Författare :Vladimir Basic; Jorge Ruas; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; COPD; cachexia; atrophy; cigarette smoke; myogenesis; angiogenesis; Biomedicin; Biomedicine; Biokemi; Biochemistry;

    Sammanfattning : Cigarette smoking (CS) represents the main causative agent underlying development and progress of COPD. Recently, involvement of CS in the pathogenesis of COPDassociated muscle abnormalities is becoming increasingly evident. Nevertheless, involved triggers and underlying mechanisms remain largely unknown. LÄS MER