Sökning: "mathias lundberg"

Hittade 3 avhandlingar innehållade orden mathias lundberg.

  1. 1. Cloning and characterization of human glutaredoxins

    Författare :Mathias Lundberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Reactive oxygen species, ROS, are generated in cells during aerobic metabolism. High and sustained levels of ROS pose a serious threat to all major cellular components, DNA, proteins mid lipids whereas controlled and physiological concentrations play a central role as a second messenger signal molecule involved in cell functions including, differentiation, proliferation, and apoptosis. LÄS MER

  3. 2. Bioimaging for analysis of protein expression in cells and tissues using affinity reagents

    Författare :Emma Lundberg; Torbjörn Gräslund; Mathias Uhlén; Rainer Pepperkok; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; Affibody; antibody; biomarker; cell line; cell microarray; colorectal cancer; confocal microscopy; HER2; immunohistochemistry; immunofluorescence; light microscopy; protein expression; protein localization; SATB2; tissue microarray; Bioengineering; Bioteknik; Cell and molecular biology; Cell- och molekylärbiologi;

    Sammanfattning : The detection and analysis of biomolecules, such as proteins, are of great interest since these molecules are fundamental for life and our health. Due to the complexity of biological processes, there is a great advantage of studying proteins in their natural context, for example by using bioimaging. LÄS MER

  4. 3. Integration of RNA and protein expression profiles to study human cells

    Författare :Frida Danielsson; Emma Lundberg; Mikael Huss; Mathias Uhlén; Christine Vogel; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; RNA-seq; Transcriptomics; Proteomics; Malignant transformation; Cancer; Functional enrichment; Bioteknologi; Biotechnology; Medical Technology; Medicinsk teknologi;

    Sammanfattning : Cellular life is highly complex. In order to expand our understanding of the workings of human cells, in particular in the context of health and disease, detailed knowledge about the underlying molecular systems is needed. LÄS MER