Sökning: "lung mechanics"

Visar resultat 31 - 35 av 56 avhandlingar innehållade orden lung mechanics.

  1. 31. Nebulized corticosteroid in septic lung injury : An experimental study in pigs

    Författare :Sten Walther; Bo Risberg; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Sepsis is occasionally complicated by the adult respiratory distress syndrome (ARDS). Auto injury by immunocompetent cells are given a central role in the pathogenesis, but our understanding of the mechanisms remains fragmentary. Treatment in septic ARDS is mainly supportive, no causal therapy exists. Mortality is high at 50-70%. LÄS MER

  3. 32. Artificial Neural Networks (ANN) in the Assessment of Respiratory Mechanics

    Författare :Gaetano Perchiazzi; Göran Hedenstierna; Björn Jonson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology; artificial neural networks; respiratory system compliance; respiratory system resistance; respiratory system time constant; intrinsic positive end expiratory pressure; PEEPi; animal model; acute lung injury; oleic acid; Otis model; Fysiologi; Physiology; Fysiologi;

    Sammanfattning : The aim of this thesis was to test the capability of Artificial Neural Networks (ANN) to estimate respiratory mechanics during mechanical ventilation (MV). ANNs are universal function approximators and can extract information from complex signals. LÄS MER

  4. 33. Regional Lung Kinetics of Ventilator-Induced Lung Injury and Protective-Ventilation Strategies Studied by Dynamic Positron Emission Tomography

    Författare :João Batista Borges; Anders Larsson; Giacomo Bellani; Uppsala universitet; []
    Nyckelord :[18F]fluoro-2-deoxy-D-glucose; positron emission tomography; acute pulmonary inflammation; acute respiratory distress syndrome; mechanical ventilation; ventilator-induced lung injury;

    Sammanfattning : Mechanical ventilation in itself can harm the lung and cause ventilator-induced lung injury (VILI), which can induce or aggravate acute respiratory distress syndrome (ARDS). Much debate remains over pivotal concepts regarding the pathophysiology of VILI, especially about the precise contribution, kinetics, and primary role of potential VILI mechanisms. LÄS MER

  5. 34. Pathophysiology and treatment of chlorine gas-induced lung injury : an experimental study in pigs

    Författare :Jianpu Wang; Kai Knudsen; Östergötlands Läns Landsting; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : One of the most threatening scenarios in disaster medicine is the accidental release of toxic gases with the exposure of many people. In this respect, chlorine gas remains a significant threat due to its abundant use and transport through densely populated areas in modem society. LÄS MER

  7. 35. Measurement of T1 relaxation time in lungs - Preclinical and clinical MRI applications to COPD

    Författare :Daniel Alamidi; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Magnetic Resonance Imaging; biomarker; tobacco smoke; mouse; smoking; lung imaging; Chronic Obstructive Pulmonary Disease; ultrashort echo time UTE ; T1 mapping; longitudinal relaxation time;

    Sammanfattning : Monitoring of regional lung function in clinical trials of chronic obstructive pulmonary disease (COPD) requires alternative endpoints beyond global pulmonary function tests (PFTs), which is the most common approach for diagnosing lung function abnormalities in humans. A promising magnetic resonance imaging (MRI) biomarker of lung disease in humans and animals is the T1 relaxation parameter. LÄS MER