Sökning: "leukocyte recruitment and adhesion"

Visar resultat 21 - 25 av 33 avhandlingar innehållade orden leukocyte recruitment and adhesion.

1. 21. The biological mechanisms in neutrophil and eosinophil adhesion and transmigration in vitro and theur relation to the inflammatory process in vivo

   Författare :Ali Moshfegh; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : In inflammatory reactions, eosinophils and neutrophils constitute the major classes of granulocytes that emigrate from the bloodstream into the tissues. The recruitment of inflammatory cells constitutes a multi-step process that includes sequential adhesion and transmigration through, the endothelial lining, the underlying basement membrane and a variety of extracellular matrix components. LÄS MER

3. 22. Leukocyte transmigration and gene expression in healthy subjects and patients with renal failure-application of the skin chamber technique

   Författare :Elham Dadfar; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Renal failure; inflammation; skin chamber technique; leukocytes; adhesion mulecules;

   Sammanfattning : The migration of leukocytes from the peripheral circulation into infected or injured tissue is a fundamental step in the host-defense mechanism. The skin chamber technique is a well documented method for studies of leukocyte trans migration and function in vivo. LÄS MER

4. 23. In vivo imaging of leukocyte-endothelium interactions in septic lung injury

   Författare :Jonas Roller; Kirurgi; []
   Nyckelord :Sepsis; Acute lung injury; Leukocyte recruitment; Intravital fluorescence microscopy;

   Sammanfattning : Excessive accumulation of leukocytes in the lung represents a key feature in the development of an acute lung injury (ALI). Numerous studies demonstrated that leukocyte rolling is a compulsory precondition for the firm adhesion in organs. However, it seems that the recruitment process of leukocytes in the lung is more complex. LÄS MER

5. 24. Expression, recognition and usage of laminin-8 (a4b1g1, Lm-411) by monocytes and neutrophils

   Författare :Zenebech Wondimu; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Basement membrane; laminins; myeloid cells; extravasation; migration.;

   Sammanfattning : Laminins (LNs) are a family of large alphabetagamma heterotrimeric glycoproteins found in all basement membranes (BMs). They are expressed in a tissue- and developmental stagespecific manner and implicated in vital cellular functions, including cell adhesion, migration and signaling. LÄS MER

7. 25. Leukocyte-endothelial interactions in arteries in vivo : a new concept in the study of physiology and disease in large blood vessels

   Författare :Einar Eriksson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Atherosclerosis; leukocyte; cell adhesion molecule; chemokine; shear rate; capture; rolling; adhesion; subendothelial; cytokine; artery; intravital; in vivo;

   Sammanfattning : Pathophysiological events in large blood vessels contribute to immense morbidity and mortality in our society. A major clinical problem is a disease known as atherosclerosis. It involves a slow inflammatory deposition of lipid within the walls of large arteries that with time will weaken the arterial wall. LÄS MER