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Visar resultat 21 - 25 av 26 avhandlingar som matchar ovanstående sökkriterier.

1. 21. Mathematical modeling of fluid and solute transport in peritoneal dialysis

   Författare :Jacek Waniewski; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :diffusion; convective transport; perfusion; lymphatic absorption; ultrafiltration; osmosis; continuous ambulatory peritoneal dialysis;

   Sammanfattning : Optimization of peritoneal dialysis schedule and dialysis fluid composition needs, among others, methods for quantitative assessment of fluid and solute transport. Furthermore, an integrative quantitative description of physiological processes within the tissue, which contribute to the net transfer of fluid and solutes, is necessary for interpretation of the data and for predictions of the outcome of possible intervention into the peritoneal transport system. LÄS MER

3. 22. Pan-cancer study of transcriptional responses to oncogenic somatic mutations

   Författare :Arghavan Ashouri; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cancer; Driver mutations; Genomics; Transcriptomics; lncRNAs; NRF2; ALK;

   Sammanfattning : Cancer cells typically carry acquired somatic mutations in key cancer driver genes, which can be identified on the basis of recurrence in cancer cohorts. Such mutations may cause aberrant protein activity and altered gene expression in the nucleus, driving the cell toward a cancerous phenotype. LÄS MER

4. 23. Exploring customer needs from a digital healthcare service

   Författare :Daan Kabel; Mattias Elg; Jason Martin; Lars Witell; Anders Fundin; Linköpings universitet; []
   Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Customer experience; Digital service quality; E-health; mHealth; Voice of the customer; Electronic word-of-mouth; Method comparison;

   Sammanfattning : Cost-effectively capturing and understanding customer needs allows a firm to stay synchronized with the market, to stay ahead of competitors, and to enable service innovation. Traditional qualitative market research methods, such as interviews and focus groups are well-known methods for identifying and capturing customer needs but can be costly, tedious, time-consuming, and can require intensive collaboration with customers. LÄS MER

5. 24. Functional neurobiology in normal aging, mild cognitive impairment and Alzheimer's disease : focus on on visuospatial processing using functional magnetic resonance imaging

   Författare :Patrizia Vannini; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Alzheimer s disease; brain function; functional magnetic resonance imaging; mild cognitive impairment; normal aging; task demand; visuospatial processing;

   Sammanfattning : With the proportional increase of the aging population in the coming decades as well as a continuously augmenting life expectancy, the effects of neurodegeneration on brain function are a topic of increasing importance. Of special interest are tools that probe the functional consequences of neurodegenerative processes and possible compensatory mechanisms that might emerge. LÄS MER

7. 25. Understanding the role of regulatory RNAs in human skin wound healing

   Författare :Letian Zhang; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Human skin wound healing is characterized by four phases in a timely manner, including hemostasis, inflammation, proliferation, and remodeling. Various cell types are involved in the biological process. LÄS MER