Sökning: "hereditary sensory and autonomic neuropathy"
Hittade 4 avhandlingar innehållade orden hereditary sensory and autonomic neuropathy.
1. Mapping genetic diseases in northern Sweden
Sammanfattning : The population of northern Sweden has previously been shown to be well suited for the mapping of monogenic diseases. In this thesis we have tested the hypothesis that this population could also be used for efficient identification of risk genes for common diseases. LÄS MER
2. A pathway for pleasant touch: linking peripheral receptors to central processing and hedonic experience
Sammanfattning : This thesis investigates the mechanisms underpinning pleasant touch, describes a pathway from peripheral nerve endings in the skin to the insular cortex, and relates these findings to the subjective hedonic experience of touch. In Paper I, the relationship between primary afferent encoding and perception of pleasantness was investigated by combining microneurography recordings from human mechanoreceptors with psychophysical measurements during soft brush stroking at 6 different velocities between 0. LÄS MER
3. Studies on the role of NGF in arthritis-induced pain transmission using gait and weight bearing as outcome measures
Sammanfattning : Pain is one of the most common reasons for seeking healthcare, with approximately forty percent of those suffering from chronic pain having joint pain. Osteoarthritis is the most common cause of joint pain, but currently there are few treatments available. LÄS MER
4. Drug discovery targeting non-amyloid pathways in Alzheimer’s disease
Sammanfattning : Alzheimer’s disease (AD) is the most common form of dementia with almost 50 million people affected and unfortunately, no cure or treatment to halt the disease progression is available. In the hereditary forms of AD, an overproduction of amyloid β (Aβ) and the Aβ plaque formation are the basis for the amyloid hypothesis of AD, while several additional factors seem to influence the likelihood to develop sporadic forms of AD. LÄS MER
