Sökning: "goblet cell"

Visar resultat 6 - 10 av 23 avhandlingar innehållade orden goblet cell.

  1. 6. Autoantigens in Inflammatory Bowel Disease and Primary Sclerosing Cholangitis

    Författare :Brita Ardesjö; Olov Ekwall; Olle Kämpe; Fredrik Rorsman; Eric Gershwin; Uppsala universitet; []
    Nyckelord :Molecular medicine; inflammatory bowel disease; primary sclerosing cholangitis; autoimmunity; autoantigen; goblet cell; Molekylärmedicin;

    Sammanfattning : Inflammatory bowel disease (IBD) comprises diseases that are characterized by chronic or relapsing inflammation of the gastrointestinal tract. Primary sclerosing cholangitis (PSC) is an extraintestinal manifestation in IBD. LÄS MER

  3. 7. A study on the role of T helper cells in allergic inflammation

    Författare :Julian Mario Stark; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Asthma is a chronic inflammatory disease of the airways affecting hundreds of millions of people worldwide. Central to the development of asthma and allergic airway inflammation are CD4 T cells, which upon activation through their T cell antigen receptor, differentiate into T helper (Th) cells with the potential to secrete distinct sets of cytokines. LÄS MER

  4. 8. The mucus layer and other barriers to intestinal drug absorption

    Författare :Agneta Wikman Larhed; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacy; FARMACI; PHARMACY; FARMACI; galenisk farmaci; Pharmaceutics;

    Sammanfattning : The extraepithelial mucus layer acts as a barrier to the absorption and diffusion of drugs. Three in vitro models have been used for studies of this and other intestinal barriers to drug transport. A drug absorption model based on monolayers of the mucus-producing human intestinal goblet HT29-H cell line was developed. LÄS MER

  5. 9. Defining the role of mast cells in guinea pig models of asthma

    Författare :Jielu Liu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Asthma is a common respiratory disease characterized by several pathophysiological features, such as allergen induced bronchoconstriction (in allergic asthma), airway hyperresponsiveness (AHR), airway inflammation, airway remodeling and mast cell hyperplasia. An increase of mast cells has been found in asthma patients. LÄS MER

  7. 10. Bestrophin-3: Localization and function in normal and injured tissues

    Författare :Veronika Golubinskaya; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bestrophin-3; alternative splicing; injury;

    Sammanfattning : Bestrophin-3 (Best3) is a protein with multiple functions. It can constitute a calcium-activated chloride channel when overexpressed in cultured cells, but the function of Best3 is not well studied in cells in situ. Recently Best3 protein was suggested to play also cell-protective role. LÄS MER