Sökning: "genetic disease models"

Visar resultat 21 - 25 av 289 avhandlingar innehållade orden genetic disease models.

  1. 21. Genetic dissection of models for neuroinflammation and neurodegeneration

    Författare :Karin Harnesk; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Many central nervous system (CNS) diseases are characterized by inflammation and nerve cell loss, but the exact relationship between these phenomena is not known. The complex etiology of CNS disorders includes a genetic component. LÄS MER

  3. 22. Genomic and genetic alterations in endometrial adenocarcinoma

    Författare :Eva Falck; Karin Klinga-Levan; Afrouz Behboudi; Pierre Åhman; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endometrial cancer; Genetic background; BDII rat model; SKY; Chromosomal abreations; Gene expression; Medicine; Medicin; Natural sciences;

    Sammanfattning : The most frequently diagnosed cancer of the female genital tract is cancer of the endometrium (endometrial cancer), ranking fourth among the invasive tumors that affect women in Europe and North America. As most other cancer types, endometrial cancer is a complex genetic disease influenced by both genetic and environmental factors. LÄS MER

  4. 23. Risk prediction models for cardiovascular disease and overall mortality

    Författare :Andrea Ganna; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Prediction or prognostication is at the core of modern evidence-based medicine. Prediction of overall mortality and cardiovascular disease can be improved by a systematic evaluation of measurements from large-scale epidemiological studies or by using nested sampling designs to discover new markers from omics technologies. LÄS MER

  5. 24. The role of MBOAT7 on fatty liver disease

    Författare :Andrea Caddeo; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Liver disease; medicine; Genetics; NAFLD;

    Sammanfattning : Non-alcoholic fatty liver disease (NAFLD) is the main health disorder in internal medicine, affecting one third of the population worldwide. Environmental and genetic factors contribute to NAFLD susceptibility and progression. LÄS MER

  7. 25. Genetic adaptations of Helicobacter pylori during gastric disease progression

    Författare :Helene Kling Bäckhed; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Helicobacter pylori colonizes the stomachs of approximately half of all humans. In the absence of treatment, H. pylori can persist throughout the life of the host. Although most infected individuals are asymptomatic, a significant proportion develops peptic ulcer disease, chronic atrophic gastritis (ChAG) or gastric adenocarcinoma. LÄS MER