Sökning: "BDII rat model"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden BDII rat model.

  1. 1. Gene Expression Patterns in a Rat Model of Human Endometrial Adenocarcinoma

    Författare :Sandra Karlsson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; rat; complex disease; Endometrial adenocarcinoma; gene expression profiling; cDNA microarrays; candidate genes; Molecular biology; Medical sciences;

    Sammanfattning : Endometrial cancer develops from the endometrium of the uterus and is the most common pelvic malignancy diagnosed in women in the western society. Similar to all cancer diseases, endometrial cancer is a disorder that results from complex patterns of genetic and epigenetic alterations involved in the malignant transformation. LÄS MER

  3. 2. Genomic and genetic alterations in endometrial adenocarcinoma

    Författare :Eva Falck; Karin Klinga-Levan; Afrouz Behboudi; Pierre Åhman; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endometrial cancer; Genetic background; BDII rat model; SKY; Chromosomal abreations; Gene expression; Medicine; Medicin; Natural sciences;

    Sammanfattning : The most frequently diagnosed cancer of the female genital tract is cancer of the endometrium (endometrial cancer), ranking fourth among the invasive tumors that affect women in Europe and North America. As most other cancer types, endometrial cancer is a complex genetic disease influenced by both genetic and environmental factors. LÄS MER

  4. 3. MicroRNA expression profiling in endometrial adenocarcinoma

    Författare :Sanja Jurcevic; Karin Klinga-Levan; Björn Olsson; Yvonne Wettergren; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endometrial cancer; microRNA; BDII rat model; normalization; endogenous controls; Medicin; Medicine;

    Sammanfattning : .... LÄS MER

  5. 4. Analyses of Rat Tumor Models for DMBA-induced Fibrosarcoma and Spontaneous Endometrial Carcinoma

    Författare :Emma Samuelson; Göteborgs universitet; []
    Nyckelord :cancer; rat models;

    Sammanfattning : Cancer is a disease of genes. Uncontrolled cell growth is the outcome from genetic as well as epigenetic alterations, resulting in a tumor cell mass that harbors a cancer genome. During progression, the tumor acquires self-dependence and the ability to invade other tissues and metastasize. LÄS MER

  7. 5. Novel Tumor Suppressor Gene Candidates in Experimental Endometrial Carcinoma - From Cytogenetic to Molecular Analysis

    Författare :Carola Hedberg; Göteborgs universitet; []
    Nyckelord :cancer; endometrial cancer; tumor suppressor gene; rat models; Skip; Myo1c;

    Sammanfattning : Endometrial carcinoma (EC) is the most common form of gynecological malignancy, ranking fourth in incidence among tumors diagnosed in women. As is the case with other complex diseases, detailed analyses of the underlying mechanisms of cancer are difficult, due mainly to the genetic heterogeneity of the human population and differences in the environment and lifestyle of individuals. LÄS MER